Syncollin Antibodies

AND Sycn ELISA kits, Syncollin Proteins

Many biological assays use antibodies to detect Syncollin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Syncollin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Syncollin antibodies...

We validate the specificity of these antibodies to Syncollin by testing them on tissues known to express Sycn positively and negatively. Browse below to find the Sycn antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Sycn Infographic by Boster Bio

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Syncollin (SYCN) (NM_001080468) Human Over-expression Lysate

Human

$628
Cat # LS342898
20 µg, 100 µg

Anti-SYCN Antibody Picoband®

Western blot analysis of SYCN using anti-SYCN antibody (A17780-1)

IF analysis of SYCN using anti-SYCN antibody (A17780-1)

Flow Cytometry analysis of K562 cells using anti-SYCN antibody (A17780-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A17780-1
100 µg/vial

Sycn Overview

Facts about Syncollin.

Syncollin (Sycn)

Functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with one another. May have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues.

Gene Information

Mouse
Gene Name:	Sycn
Uniprot:	Q8VCK7
Entrez:	68416

Family

Belongs to:

No superfamily

Alternative Names

INSSA1; insulin synthesis associated 1; Insulin synthesis-associated protein 1; SYLFLJ27441; syncollin

Molecular Weight

Mass (kDA):
14.595 kDA

Genomic Context


Mouse

Location:	7\|7 B1
Sequence:	7;

Diseases

Adenocarcinoma
Pancreatitis
Malignant Neoplasms
Pancreatic Neoplasm
Malignant Neoplasm Of Pancreas
Physiological Hyperprolactinemia
Vertigo
Pancreatic Adenocarcinoma
Hyperprolactinemia
Columnar Cell Hyperplasia Of The Breast

Carcinoma, Pancreatic Ductal
Neoplasms
Chimera Disorder
Ductal Breast Carcinoma

Pathways

Exocytosis
Secretion
Localization
Transport
Insulin Secretion
Secretory Pathway
Intracellular Transport
Membrane Depolarization
Feeding Behavior

Transcytosis
Corticotropin Secretion
Membrane Fusion

PTMs

Sulphation
Biotinylation

Cleavage
Gpi Anchoring

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Sycn

References

PMID: 11839820 by Antonin W., et al. Loss of the zymogen granule protein syncollin affects pancreatic protein synthesis and transport but not secretion.

PMID: 15040787 by Waesle B., et al. Syncollin inhibits regulated corticotropin secretion from AtT-20 cells through a reduction in the secretory vesicle population.