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Synaptotagmin-6 Antibodies
AND Syt6 ELISA kits, Synaptotagmin-6 Proteins
Many biological assays use antibodies to detect Synaptotagmin-6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Synaptotagmin-6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Synaptotagmin-6 antibodies...
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Syt6 Infographic by Boster Bio
All Syt6 Products
Product
Figures
Specificity
Applications
Price
Human
$628
Cat # LS148281
20 µg, 100 µg
Cat # LS148281
20 µg, 100 µg
Syt6 Overview
Facts about Synaptotagmin-6.
Synaptotagmin-6 (Syt6)
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity). May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm (PubMed:15774481).
.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Syt6 |
| Uniprot: | Q9R0N8 |
| Entrez: | 54524 |
Family
| Belongs to: |
|---|
| synaptotagmin family |
Alternative Names
synaptotagmin-6; sytVI
Molecular Weight
Mass (kDA):
57.204 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 3|3 F2.2 |
| Sequence: | 3; |
Tissue Specificity
Isoform 1 is expressed in the olfactory bulb. Isoform 2 is expressed in the brain (at protein level).
Diseases
- Malignant Neoplasms
- Neoplasms
- Ischemic Stroke
- Ischemia
- Nerve Degeneration
- Kidney Neoplasm
- Diabetes Mellitus
- Carcinoma
- Conventional (clear Cell) Renal Cell Carcinoma
- Heart Diseases
- Cerebrovascular Accident
Pathways
- Exocytosis
- Acrosome Reaction
- Secretion
- Membrane Fusion
- Methylation
- Synaptic Vesicle Exocytosis
- Gene Silencing
- Fertilization
- Dna Methylation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Syt6
bosterbio.com/bosterbio-gene-info-cards/Syt6
References
PMID: 10531343 by Fukuda M., et al. Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X.
PMID: 10531344 by Fukuda M., et al. A novel alternatively spliced variant of synaptotagmin VI lacking a transmembrane domain. Implications for distinct functions of the two isoforms.