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Heparin cofactor 2 Antibodies
AND SERPIND1 ELISA kits, Heparin cofactor 2 Proteins
Many biological assays use antibodies to detect Heparin cofactor 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Heparin cofactor 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Heparin cofactor 2 antibodies...
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SERPIND1 Infographic by Boster Bio
All SERPIND1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK1968
96 wells/kit, with removable strips.
Cat # EK1968
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK1969
96 wells/kit, with removable strips.
Cat # EK1969
96 wells/kit, with removable strips.
Rat
ELISA
$499
Cat # EK1970
96 wells/kit, with removable strips.
Cat # EK1970
96 wells/kit, with removable strips.
SDS-PAGE, Denatured
$250
Cat # PROTP05546
Starting from 20ug
Cat # PROTP05546
Starting from 20ug
SERPIND1 Overview
Facts about Heparin cofactor 2.
Heparin cofactor 2 (SERPIND1)
Thrombin inhibitor activated from the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III).
Also inhibits chymotrypsin, but in a glycosaminoglycan-independent method. .
Gene Information
| Human | |
|---|---|
| Gene Name: | SERPIND1 |
| Uniprot: | P05546 |
| Entrez: | 3053 |
Family
| Belongs to: |
|---|
| serpin family |
Alternative Names
HC2; HC2LS2; HCF2; HCF2clade D (heparin cofactor), member 1; HC-II; Heparin Cofactor II; HLS2HCII; leuserpin 2; LS2; Protease inhibitor leuserpin-2; Serpin D1; serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Molecular Weight
Mass (kDA):
57.071 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q11.21 |
| Sequence: | 22; NC_000022.11 (20774113..20787720) |
Tissue Specificity
Expressed predominantly in liver. Also present in plasma.
Diseases
- Atherosclerosis
- Cardiovascular Diseases
- Malignant Neoplasms
- Dental Plaque
- Blood Coagulation Disorders
- Thrombosis
- Schizoaffective Disorder
- Neoplasm Metastasis
- Infarction
- Pulmonary Embolism
- Malignant Neoplasm Of Lung
- Inflammatory Response
Pathways
- Coagulation
- Osteoclast Differentiation
- Growth Hormone Secretion
- Tube Formation
- Angiogenesis
- Regulation Of Angiogenesis
- Bone Resorption
- Hormone Secretion
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SERPIND1
bosterbio.com/bosterbio-gene-info-cards/SERPIND1
References
PMID: 2894851 by Blinder M.A., et al. Heparin cofactor II: cDNA sequence, chromosome localization, restriction fragment length polymorphism, and expression in Escherichia coli.
PMID: 1671335 by Herzog R., et al. Complete nucleotide sequence of the gene for human heparin cofactor II and mapping to chromosomal band 22q11.