Sgip1 Antibodies

AND Sgip1 ELISA kits, Sgip1 Proteins

Many biological assays use antibodies to detect Sgip1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sgip1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sgip1 antibodies...

We validate the specificity of these antibodies to Sgip1 by testing them on tissues known to express Sgip1 positively and negatively. Browse below to find the Sgip1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Sgip1 Infographic by Boster Bio

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Sgip1 Overview

Facts about SH3-containing GRB2-like protein 3-interacting protein 1.

SH3-containing GRB2-like protein 3-interacting protein 1 (Sgip1)

May function in clathrin-mediated endocytosis. Has a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits.

Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin.

Gene Information

Mouse
Gene Name:	Sgip1
Uniprot:	Q8VD37
Entrez:	73094

Family

Belongs to:

No superfamily

Alternative Names

DKFZp686A16142; DKFZp761D221; SH3-domain GRB2-like (endophilin) interacting protein 1

Molecular Weight

Mass (kDA):
86.063 kDA

Genomic Context


Mouse

Location:	4\|4 C6
Sequence:	4;

Tissue Specificity

Detected in brain, spinal cord and cerebellum.

Diseases

Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Obesity
Anxiety Disorders
Diabetic Retinopathy
Schizophrenia
Down Syndrome
Mental Disorders
Metabolic Syndrome X

Diabetes Mellitus, Experimental
Inflammation
Retinal Diseases

Pathways

Endocytosis
Clathrin-mediated Endocytosis
Transport
Bioluminescence
Regulation Of Energy Homeostasis
Energy Homeostasis

Localization

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Sgip1

References

PMID: 17626015 by Uezu A., et al. SGIP1alpha is an endocytic protein that directly interacts with phospholipids and Eps15.

PMID: 15919751 by Trevaskis J., et al. Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1, a novel neuronal protein that regulates energy balance.