Sh2d1b2 Antibodies

AND Sh2d1b2 ELISA kits, Sh2d1b2 Proteins

Many biological assays use antibodies to detect Sh2d1b2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sh2d1b2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sh2d1b2 antibodies...

We validate the specificity of these antibodies to Sh2d1b2 by testing them on tissues known to express Sh2d1b2 positively and negatively. Browse below to find the Sh2d1b2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Sh2d1b2 Infographic by Boster Bio

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Sh2d1b2 Overview

Facts about SH2 domain-containing protein 1B2.

Sh2d1b2 3D structure. Source: alphafold

SH2 domain-containing protein 1B2 (Sh2d1b2)

Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family. In SLAM signaling may cooperate with Sh2d1a/SAP.

Plays a role in regulation of effector functions of natural killer (NK) cells by controlling signal transduction through Cd244/2b4. However, conflicting results are reported which may reflect the use of different strain backgrounds.

Gene Information

Mouse
Gene Name:	Sh2d1b2
Uniprot:	Q45HK4
Entrez:	545378

Family

Belongs to:

No superfamily

Alternative Names

SH2 domain-containing protein 1B2

Molecular Weight

Mass (kDA):
15.044 kDA

Genomic Context


Mouse

Location:	1\|1 H3
Sequence:	1;

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Sh2d1b2

References

PMID: 16127454 by Roncagalli R., et al. Negative regulation of natural killer cell function by EAT-2, a SAP- related adaptor.

PMID: 16425036 by Calpe S., et al. Identification and characterization of two related murine genes, Eat2a and Eat2b, encoding single SH2-domain adapters.