This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Protein shisa-6 Antibodies
AND Shisa6 ELISA kits, Protein shisa-6 Proteins
Many biological assays use antibodies to detect Protein shisa-6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein shisa-6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein shisa-6 antibodies...
Designing a Western blot for Protein shisa-6? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SHISA6 Western Blot GuideShisa6 Infographic by Boster Bio
All Shisa6 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A14975-1
100 μg/vial
Cat # A14975-1
100 μg/vial
Shisa6 Overview
Facts about Protein shisa-6.
Protein shisa-6 (Shisa6)
Involved in maintenance of high-frequency synaptic transmission in hippocampal CA3-CA1 synapses. Regulates AMPA-type glutamate receptor (AMPAR) immobilization in postsynaptic density keeping the stations in an activated state in the presence of glutamate and preventing neurological depression (PubMed:26931375).
May play a role in self-renewal and differentiation of spermatogonial stem cells by inhibiting canonical Wnt signaling pathway (PubMed:28196692). .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Shisa6 |
| Uniprot: | Q3UH99 |
| Entrez: | 380702 |
Family
| Belongs to: |
|---|
| shisa family |
Alternative Names
shisa homolog 6 (Xenopus laevis)
Molecular Weight
Mass (kDA):
58.426 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 11|11 B3 |
| Sequence: | 11; |
Tissue Specificity
Highly expressed in cerebellum and hippocampal neurons: CA1 stratum oriens and stratum radiatum, CA3 stratum oriens and stratum lucidum, and the dentate gyrus polymorphic layer (PubMed:26931375). Expressed in other brain structures including olfactory bulb, cortex, amigdala and midbrain (at protein level) (PubMed:26623514, PubMed:26931375). Also expressed in a subset of spermatogonial stem cells (PubMed:28196692). Also expressed in eye, heart, kidney, lung, muscle and spleen. Isoform 2: Specifically expressed in hippocampus (PubMed:26931375).
PTMs
- Glycoprotein
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Shisa6
bosterbio.com/bosterbio-gene-info-cards/Shisa6
References
PMID: 26623514 by Farrow P., et al. Auxiliary subunits of the CKAMP family differentially modulate AMPA receptor properties.
PMID: 26931375 by Klaassen R.V., et al. Shisa6 traps AMPA receptors at postsynaptic sites and prevents their desensitization during synaptic activity.