Sialate O-acetylesterase Antibodies

AND Siae ELISA kits, Sialate O-acetylesterase Proteins

Many biological assays use antibodies to detect Sialate O-acetylesterase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sialate O-acetylesterase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sialate O-acetylesterase antibodies...

We validate the specificity of these antibodies to Sialate O-acetylesterase by testing them on tissues known to express Siae positively and negatively. Browse below to find the Siae antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Sialate O-acetylesterase? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SIAE IHC Guide

Siae Infographic by Boster Bio

All Siae Products

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Specificity

Applications

Price

Anti-SIAE Antibody Picoband®

Western blot analysis of SIAE using anti-SIAE antibody (A08046)

IHC analysis of SIAE using anti-SIAE antibody (A08046)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A08046
100 μg/vial

SIAE (NM_170601) Human Over-expression Lysate

Human

$628
Cat # LS054414
20 µg, 100 µg

Siae Overview

Facts about Sialate O-acetylesterase.

Sialate O-acetylesterase (Siae)

Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. .

Gene Information

Mouse
Gene Name:	Siae
Uniprot:	P70665
Entrez:	22619

Family

Belongs to:

No superfamily

Alternative Names

AIS6; CSEC; CSE-C; cytosolic sialic acid 9-O-acetylesterase homolog; EC 3.1.1.53; H-Lse; LSE; MGC87009; sialate O-acetylesterase; sialic acid acetylesterase; Sialic acid-specific 9-O-acetylesterase; sialic acid-specific acetylesterase II; Ysg2 homolog (mouse); YSG2

Molecular Weight

Mass (kDA):
60.775 kDA

Genomic Context


Mouse

Location:	9 A4\|9 20.79 cM
Sequence:	9;

Tissue Specificity

Isoform 1 is widely expressed. Isoform 2 shows a more restricted distribution with highest expression in brain and ovary and lower levels in liver and thymus.

Diseases

Autoimmune Reaction
Autoimmune Diseases
Autoimmunity
Diabetes Mellitus
Arteriovenous Malformation
Hemorrhage
Diabetes Mellitus, Insulin-dependent
Cell Invasion
Biliary Cirrhosis
Graves Disease
Pre-eclampsia
Acute Lymphocytic Leukemia
Immunologic Tolerance

Addison's Disease Due To Autoimmunity
Primary Biliary Cirrhosis
Arthritis
Addison Disease
Leukemia
Inflammation
L1 Acute Lymphoblastic Leukemia

Pathways

Pathogenesis
Secretion

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Siae

References

PMID: 8918804 by Stoddart A., et al. Molecular cloning of the cDNA encoding a murine sialic acid-specific 9-O-acetylesterase and RNA expression in cells of hematopoietic and non-hematopoietic origin.

PMID: 8662838 by Guimaraes M.J., et al. Molecular cloning and characterization of lysosomal sialic acid O- acetylesterase.