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- Table of Contents
SMARCC1 Antibodies
AND SMARCC1 ELISA kits, SMARCC1 Proteins
Many biological assays use antibodies to detect SMARCC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SMARCC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SMARCC1 antibodies...
Designing a Western blot for SMARCC1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SMARCC1 Western Blot GuideSMARCC1 Infographic by Boster Bio
All SMARCC1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, WB
$370
Cat # A03303-3
100 μg/vial
Cat # A03303-3
100 μg/vial
Human, Rat
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M03303-1
100 μl/vial
Cat # M03303-1
100 μl/vial
SMARCC1 Overview
Facts about SWI/SNF complex subunit SMARCC1.
SWI/SNF complex subunit SMARCC1 (SMARCC1)
Component of SWI/SNF chromatin remodeling complexes that carry out crucial enzymatic actions, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. May stimulate the ATPase activity of the catalytic subunit of the complex (PubMed:10078207, PubMed:29374058).
Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron- specific chromatin remodeling complex (nBAF complex). During neural development a change from a stem/progenitor into a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become dedicated to their adult condition.
Gene Information
| Human | |
|---|---|
| Gene Name: | SMARCC1 |
| Uniprot: | Q92922 |
| Entrez: | 6599 |
Family
| Belongs to: |
|---|
| SMARCC family |
Alternative Names
BAF155SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily C member 1; BRG1-associated factor 155; chromatin remodeling complex BAF155 subunit; CRACC1; mammalian chromatin remodeling complex BRG1-associated factor 155; Rsc8; SRG3; subfamily c, member 1; SWI/SNF complex 155 kDa subunit; SWI/SNF complex subunit SMARCC1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin; SWI3
Molecular Weight
Mass (kDA):
122.867 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p21.31 |
| Sequence: | 3; NC_000003.12 (47585269..47781893, complement) |
Tissue Specificity
Expressed in brain, heart, muscle, placenta, lung, liver, muscle, kidney and pancreas.
Subcellular Localizations
Nucleus. Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Adenocarcinoma
- Cell Transformation, Neoplastic
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Thymoma
- Mammary Neoplasms
- Anaplasia
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
Interacting Proteins
- CARM1
- KDM1A
- OTX1
- PLSCR1
- SMARCA4
- SMARCD1
Pathways
- Chromatin Remodeling
- Atp-dependent Chromatin Remodeling
- Cell Cycle
- Cell Proliferation
- Cell Development
- Cell Death
- Dedifferentiation
- Cell Activation
- T Cell Activation
- Brain Development
- Fertilization
- Hypersensitivity
- Neurogenesis
PTMs
- Phosphorylation
- Ubiquitination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SMARCC1
bosterbio.com/bosterbio-gene-info-cards/SMARCC1
References
PMID: 8804307 by Wang W., et al. Diversity and specialization of mammalian SWI/SNF complexes.
PMID: 9744861 by Sif S., et al. Mitotic inactivation of a human SWI/SNF chromatin remodeling complex.