Supt4h1b Antibodies

AND Supt4h1b ELISA kits, Supt4h1b Proteins

Many biological assays use antibodies to detect Supt4h1b, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Supt4h1b in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Supt4h1b antibodies...

We validate the specificity of these antibodies to Supt4h1b by testing them on tissues known to express Supt4h1b positively and negatively. Browse below to find the Supt4h1b antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Supt4h1b Infographic by Boster Bio

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Supt4h1b Overview

Facts about Transcription elongation factor SPT4-B.

Supt4h1b 3D structure. Source: alphafold

Transcription elongation factor SPT4-B (Supt4h1b)

Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A.

DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex.

Gene Information

Mouse
Gene Name:	Supt4h1b
Uniprot:	Q9Z199
Entrez:

Family

Belongs to:

SPT4 family

Alternative Names

Transcription elongation factor SPT4-B

Molecular Weight

Mass (kDA):
13.194 kDA

Genomic Context


Mouse

Location:
Sequence:	;

Tissue Specificity

Expressed in brain, heart and liver.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Supt4h1b

References

PMID: 9776760 by Chiang P.-W., et al. Comparison of murine Supt4h and a nearly identical expressed, processed gene: evidence of sequence conservation through gene conversion extending into the untranslated regions.