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- Table of Contents
Facts about Rho GTPase-activating protein SYDE1.
GTPase activator for the Rho-type GTPases.
As a GCM1 downstream effector, it's involved in placental growth and positively regulates trophoblast cells migration.It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1. .
| Mouse | |
|---|---|
| Gene Name: | Syde1 |
| Uniprot: | Q9DBZ9 |
| Entrez: | 71709 |

| Belongs to: |
|---|
| No superfamily |

EC 2.4.1.25; EC 2.6.1.9; FLJ13511; Protein syd-1 homolog 1; rho GTPase-activating protein SYDE1; synapse defective 1, Rho GTPase, homolog 1 (C. elegans); Synapse defective protein 1 homolog 1,7h3
Mass (kDA):
80.496 kDA

| Mouse | |
|---|---|
| Location: | 10|10 C1 |
| Sequence: | 10; |



PMID: 27917469 by Lo H.F., et al. Association of dysfunctional synapse defective 1 (SYDE1) with restricted fetal growth - SYDE1 regulates placental cell migration and invasion.