Rho GTPase-activating protein SYDE1 (Syde1)

GTPase activator for the Rho-type GTPases.

As a GCM1 downstream effector, it's involved in placental growth and positively regulates trophoblast cells migration.

It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1. .