Syncytin-B Antibodies

AND Synb ELISA kits, Syncytin-B Proteins

Many biological assays use antibodies to detect Syncytin-B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Syncytin-B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Syncytin-B antibodies...

We validate the specificity of these antibodies to Syncytin-B by testing them on tissues known to express Synb positively and negatively. Browse below to find the Synb antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Synb Infographic by Boster Bio

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Synb Overview

Facts about Syncytin-B.

Synb 3D structure. Source: alphafold

Syncytin-B (Synb)

This endogenous retroviral envelope protein has retained its original fusogenic properties (PubMed:15644441, PubMed:18077339, PubMed:22032925, PubMed:27589388). Together with Syna, participates in trophoblast fusion and the formation of a syncytium through placenta morphogenesis (PubMed:22032925).

Synb is specially involved in formation of syncytiotrophoblast layer II (SynT-II) (PubMed:22032925). Promotes myoblast fusion, and might play a role in regeneration of damaged muscle tissue in males (PubMed:27589388).

Gene Information

Mouse
Gene Name:	Synb
Uniprot:	Q8BI41
Entrez:	239167

Family

Belongs to:

gamma type-C retroviral envelope protein family

Alternative Names

Syncytin-B

Molecular Weight

Mass (kDA):
69.514 kDA

Genomic Context


Mouse

Location:	14\|14 D2
Sequence:	14;

Tissue Specificity

Highly expressed in placenta where it localizes to syncytiotrophoblasts of the labyrinthine zona (PubMed:15644441). Specifically localizes to syncytiotrophoblast layer II (SynT-II) (PubMed:18448564). Also detected at very low levels in ovary (PubMed:15644441).

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Synb

References

PMID: 15644441 by Dupressoir A., et al. Syncytin-A and syncytin-B, two fusogenic placenta-specific murine envelope genes of retroviral origin conserved in Muridae.

PMID: 18077339 by Mangeney M., et al. Placental syncytins: Genetic disjunction between the fusogenic and immunosuppressive activity of retroviral envelope proteins.