Synaptotagmin-6 Antibodies

AND Syt6 ELISA kits, Synaptotagmin-6 Proteins

Many biological assays use antibodies to detect Synaptotagmin-6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Synaptotagmin-6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Synaptotagmin-6 antibodies...

We validate the specificity of these antibodies to Synaptotagmin-6 by testing them on tissues known to express Syt6 positively and negatively. Browse below to find the Syt6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Syt6 Infographic by Boster Bio

All Syt6 Products

Product

Figures

Specificity

Applications

Price

Anti-Synaptotagmin-6 SYT6 Antibody

Human, Mouse, Rat

$405
Cat # A12265
100ul

Synaptotagmin VI (SYT6) (NM_205848) Human Recombinant Protein

$1249
Cat # PROTQ5T7P8
20 µg

Synaptotagmin VI (SYT6) (NM_205848) Human Over-expression Lysate

Human

$628
Cat # LS148281
100 µg

Syt6 Overview

Facts about Synaptotagmin-6.

Synaptotagmin-6 (Syt6)

May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity). May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm (PubMed:15774481).

Gene Information

Mouse
Gene Name:	Syt6
Uniprot:	Q9R0N8
Entrez:	54524

Family

Belongs to:

synaptotagmin family

Alternative Names

synaptotagmin-6; sytVI

Molecular Weight

Mass (kDA):
57.204 kDA

Genomic Context


Mouse

Location:	3\|3 F2.2
Sequence:	3;

Tissue Specificity

Isoform 1 is expressed in the olfactory bulb. Isoform 2 is expressed in the brain (at protein level).

Diseases

Malignant Neoplasms
Neoplasms
Ischemic Stroke
Ischemia
Nerve Degeneration
Kidney Neoplasm
Diabetes Mellitus
Carcinoma
Conventional (clear Cell) Renal Cell Carcinoma
Heart Diseases
Cerebrovascular Accident

Nervousness
Colorectal Neoplasms
Renal Cell Carcinoma
Colorectal Cancer
Multiple Acyl Coenzyme A Dehydrogenase Deficiency

Pathways

Exocytosis
Acrosome Reaction
Secretion
Membrane Fusion
Methylation
Synaptic Vesicle Exocytosis
Gene Silencing
Fertilization
Dna Methylation

Endocytosis
Localization
Vesicle Fusion
Reverse Transcription

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Syt6

References

PMID: 10531343 by Fukuda M., et al. Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X.

PMID: 10531344 by Fukuda M., et al. A novel alternatively spliced variant of synaptotagmin VI lacking a transmembrane domain. Implications for distinct functions of the two isoforms.