Synaptotagmin-8 Antibodies

AND Syt8 ELISA kits, Synaptotagmin-8 Proteins

Many biological assays use antibodies to detect Synaptotagmin-8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Synaptotagmin-8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Synaptotagmin-8 antibodies...

We validate the specificity of these antibodies to Synaptotagmin-8 by testing them on tissues known to express Syt8 positively and negatively. Browse below to find the Syt8 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Syt8 Infographic by Boster Bio

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Anti-Synaptotagmin-8 SYT8 Antibody

Western blot (WB) analysis of SYT8 polyclonal antibody at 1:500 dilution
Lane1:HEK293T whole cell lysate
Lane2:Raw264

Human, Mouse, Rat

$405
Cat # A12547
100ul

SYT8 (NM_138567) Human Over-expression Lysate

Human

$628
Cat # LS090019
20 µg, 100 µg

Syt8 Overview

Facts about Synaptotagmin-8.

Synaptotagmin-8 (Syt8)

Involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Mediates Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.

May mediate Ca(2+)- regulation of exocytosis in cells. .

Gene Information

Mouse
Gene Name:	Syt8
Uniprot:	Q9R0N6
Entrez:	55925

Family

Belongs to:

synaptotagmin family

Alternative Names

DKFZp434K0322; Synaptotagmin VIII; Synaptotagmin-8; SYT8; SytVIII

Molecular Weight

Mass (kDA):
44.093 kDA

Genomic Context


Mouse

Location:	7\|7 F5
Sequence:	7;

Tissue Specificity

Ubiquitous. Detected in testis and brain. Expressed in primary neurons, neuroendocrine and endocrine cells.

Diseases

Diabetes Mellitus
Disease Of Adrenal Medulla

Pathways

Exocytosis
Secretion
Membrane Fusion
Endocytosis
Localization
Acrosome Reaction
Transport
Insulin Secretion
Regulation Of Gene Expression

Vesicle Fusion
Regulation Of Transport
Synaptic Vesicle Exocytosis
Chromatin Organization

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Syt8

References

PMID: 10531343 by Fukuda M., et al. Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X.

PMID: 7791877 by Li C., et al. Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins.