Tachykinin-3 Antibodies

AND TAC3 ELISA kits, Tachykinin-3 Proteins

Many biological assays use antibodies to detect Tachykinin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tachykinin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tachykinin-3 antibodies...

We validate the specificity of these antibodies to Tachykinin-3 by testing them on tissues known to express TAC3 positively and negatively. Browse below to find the TAC3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TAC3 Infographic by Boster Bio

All TAC3 Products

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Specificity

Applications

Price

Anti-Tachykinin-3 TAC3 Antibody

Western blot analysis of extracts of various cell lines, using TAC3 antibody at 1:1000 dilution

Immunofluorescence analysis of mouse brain cells using TAC3 Rabbit pAb at dilution of 1:100

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A05391
100ul

Neurokinin B (TAC3) (NM_013251) Human Recombinant Protein

Coomassie blue staining of purified TAC3 protein

$1249
Cat # PROTQ9UHF0
20 µg

Neurokinin B (TAC3) (NM_013251) Human Over-expression Lysate

Human

$628
Cat # LS006866
20 µg, 100 µg

TAC3 Overview

Facts about Tachykinin-3.

TAC3 3D structure. Source: alphafold

Tachykinin-3 (TAC3)

Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles (By similarity). Is a critical central regulator of gonadal function.

Gene Information

Human
Gene Name:	TAC3
Uniprot:	Q9UHF0
Entrez:	6866

Family

Belongs to:

tachykinin family

Alternative Names

gamma tachykinin 3; neurokinin beta; neurokinin B-like; neuromedin K; preprotachykinin B; PRO1155; tachykinin 3; tachykinin-3; ZNEUROK1NKNBNKB

Molecular Weight

Mass (kDA):
13.438 kDA

Genomic Context


Human

Location:	12q13.3
Sequence:	12; NC_000012.12 (57010000..57016529, complement)

Subcellular Localizations

Secreted.

Diseases

Hypogonadotropic Hypogonadism
Hypogonadism
Kallmann Syndrome
Idiopathic Hypogonadotropic Hypogonadism
Anosmia
Pituitary Diseases
Olfaction Disorders
Amenorrhea
Neoplasm Metastasis
Malignant Neoplasms
Ovarian Neoplasm
Hereditary Diseases
Delayed Puberty

Malignant Neoplasm Of Ovary
Chronic Constipation
Sclerosis
Charge Syndrome
Malnutrition
Mutation, Out-of-frame
Central Nervous System Inflammation

Interacting Proteins

TACR3

Pathways

Secretion
Sperm Motility
Gonadotropin Secretion
Hormone Secretion
Developmental Process
Localization
Inflammatory Response
Senescence
Thelarche
Neuron Migration

Regulation Of Sperm Motility
Cell Growth
Estrus
Pathogenesis

PTMs

Amidation

Cleavage on pair of basic residues

Research Areas

GPCR
Neuroscience
Neurotransmission

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TAC3

References

PMID: 10866201 by Page N.M., et al. Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia.

PMID: 19079066 by Topaloglu A.K., et al. TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction.