Tachykinin-4 Antibodies

AND Tac4 ELISA kits, Tachykinin-4 Proteins

Many biological assays use antibodies to detect Tachykinin-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tachykinin-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tachykinin-4 antibodies...

We validate the specificity of these antibodies to Tachykinin-4 by testing them on tissues known to express Tac4 positively and negatively. Browse below to find the Tac4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Tac4 Infographic by Boster Bio

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TAC4 (NM_170685) Human Over-expression Lysate

Human

$628
Cat # LS255061
20 µg, 100 µg

Tac4 Overview

Facts about Tachykinin-4.

Tachykinin-4 (Tac4)

Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Hemokinin induces plasma extravasation, mast cell degranulation, muscle contraction, salivary secretion and scratching behavior.

Increases sperm motility. Induces potent analgesic effects and might play a role in pain modulation.

Gene Information

Mouse
Gene Name:	Tac4
Uniprot:	Q99N14
Entrez:	93670

Family

Belongs to:

tachykinin family

Alternative Names

Tachykinin-4

Molecular Weight

Mass (kDA):
13.937 kDA

Genomic Context


Mouse

Location:	11\|11 D
Sequence:	11;

Tissue Specificity

Expressed in hematopoietic cells with highest levels in pre- and pro-B cells but not in later developmental stages. Also detected in uterus, skeletal muscle, brain, spleen, stomach, skin and lactating mammary gland and in cells of myeloid lineage including dendritic and microglial cells and macrophages. In uterus, highest expression is observed in non-pregnant diestrus mice and in day 5 pregnant mice. Compared with mice in diestrus, decreases 2.6-fold in uteri from non-pregnant mice in estrus and 10.2-fold in day 17 pregnant mice. Detected at sites of chronic inflammation such as granulomas.

PTMs

Amidation

Cleavage on pair of basic residues

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Tac4

References

PMID: 11062498 by Zhang Y., et al. Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis.

PMID: 12716968 by Page N.M., et al. Characterization of the endokinins: human tachykinins with cardiovascular activity.