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- Table of Contents
Facts about TBC1 domain family member 25.
Acts as a GTPase-activating protein specific for RAB33B.
Involved in the regulation of autophagosome maturation, the procedure in which autophagosomes fuse with endosomes and lysosomes..
| Human | |
|---|---|
| Gene Name: | TBC1D25 |
| Uniprot: | Q3MII6 |
| Entrez: | 4943 |

| Belongs to: |
|---|
| No superfamily |

MG81; MGC126866; MGC126868; MGC149732; OATL1MGC149731; ornithine aminotransferase-like 1; TBC1 domain family member 25; TBC1 domain family, member 25
Mass (kDA):
76.327 kDA

| Human | |
|---|---|
| Location: | Xp11.23 |
| Sequence: | X; NC_000023.11 (48539619..48562609) |
Cytoplasm. Cytoplasmic vesicle, autophagosome. It is dispersed in the cytoplasm under nutrient-rich conditions. Localizes at autophagosomes under cell starving conditions.



PMID: 21383079 by Itoh T., et al. OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation.