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- Table of Contents
Facts about Tubulin-folding cofactor B.
May function as a negative regulator of axonal growth (By similarity). .
Human | |
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Gene Name: | TBCB |
Uniprot: | Q99426 |
Entrez: | 1155 |
Belongs to: |
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TBCB family |
CG22Tubulin-specific chaperone B; CKAP1MGC14625; CKAPI; cytoskeleton associated protein 1; Cytoskeleton-associated protein 1Cytoskeleton-associated protein CKAPI; tubulin folding cofactor B; tubulin-folding cofactor B
Mass (kDA):
27.326 kDA
Human | |
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Location: | 19q13.12 |
Sequence: | 19; NC_000019.10 (36114986..36125948) |
Found in most tissues.
Cytoplasm. Cytoplasm, cytoskeleton. Colocalizes with microtubules. In differentiated neurons, located in the cytoplasm. In differentiating neurons, accumulates at the growth cone.
PMID: 9265649 by Tian G., et al. Tubulin subunits exist in an activated conformational state generated and maintained by protein cofactors.
PMID: 8978778 by Watanabe T.K., et al. Cloning, expression, and mapping of CKAPI, which encodes a putative cytoskeleton-associated protein containing a CAP-Gly domain.