TBCB Antibodies

AND TBCB ELISA kits, TBCB Proteins

Many biological assays use antibodies to detect TBCB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TBCB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TBCB antibodies...

We validate the specificity of these antibodies to TBCB by testing them on tissues known to express TBCB positively and negatively. Browse below to find the TBCB antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TBCB Infographic by Boster Bio

All TBCB Products

Product

Figures

Specificity

Applications

Price

Anti-Tubulin-folding cofactor B TBCB Antibody

Human

$405
Cat # A07032
100ul

Anti-Tubulin-folding cofactor B TBCB Antibody

Human, Mouse

ELISA, WB

$380
Cat # A07032-1
100ul

CKAP1 (TBCB) (NM_001281) Human Recombinant Protein

$1249
Cat # PROTQ99426
20 µg

CKAP1 (TBCB) (NM_001281) Human Over-expression Lysate

Human

$628
Cat # LS001155
100 µg

TBCB Overview

Facts about Tubulin-folding cofactor B.

TBCB 3D structure. Source: alphafold

Tubulin-folding cofactor B (TBCB)

Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to correctly folded heterodimer (PubMed:9265649). Involved in regulation of tubulin heterodimer dissociation.

May function as a negative regulator of axonal growth (By similarity). .

Gene Information

Human
Gene Name:	TBCB
Uniprot:	Q99426
Entrez:	1155

Family

Belongs to:

TBCB family

Alternative Names

CG22Tubulin-specific chaperone B; CKAP1MGC14625; CKAPI; cytoskeleton associated protein 1; Cytoskeleton-associated protein 1Cytoskeleton-associated protein CKAPI; tubulin folding cofactor B; tubulin-folding cofactor B

Molecular Weight

Mass (kDA):
27.326 kDA

Genomic Context


Human

Location:	19q13.12
Sequence:	19; NC_000019.10 (36114986..36125948)

Tissue Specificity

Found in most tissues.

Subcellular Localizations

Cytoplasm. Cytoplasm, cytoskeleton. Colocalizes with microtubules. In differentiated neurons, located in the cytoplasm. In differentiating neurons, accumulates at the growth cone.

Diseases

Neurodegenerative Disorders
Giant Axonal Neuropathy 1
Lissencephaly
Cell Invasion
Neuroblastoma
Malnutrition
Malformations Of Cortical Development
Haploinsufficiency
Malignant Neoplasms

Polymicrogyria
Nervousness
Ectopic Tissue

Interacting Proteins

GAN
USP7

Pathways

Microtubule Depolymerization
Gene Silencing
Neurogenesis
Transport
Cell Death
Mitosis
Microglia Differentiation

Pathogenesis
Localization

PTMs

Acetylation

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TBCB

References

PMID: 9265649 by Tian G., et al. Tubulin subunits exist in an activated conformational state generated and maintained by protein cofactors.

PMID: 8978778 by Watanabe T.K., et al. Cloning, expression, and mapping of CKAPI, which encodes a putative cytoskeleton-associated protein containing a CAP-Gly domain.