Telethonin Antibodies

AND TCAP ELISA kits, Telethonin Proteins

Many biological assays use antibodies to detect Telethonin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Telethonin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Telethonin antibodies...

We validate the specificity of these antibodies to Telethonin by testing them on tissues known to express TCAP positively and negatively. Browse below to find the TCAP antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TCAP Infographic by Boster Bio

All TCAP Products

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Applications

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Anti-Telethonin (TCAP) Mouse Monoclonal Antibody [Clone ID: OTI3E7]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCAP (Right lane) cDNA for 48 hrs and lysed

Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TCAP mouse monoclonal antibody

Human, Mouse

IHC, WB

$523
Cat # M03590
100 µl

Telethonin (TCAP) (NM_003673) Human Over-expression Lysate

Human

$628
Cat # LS008557
20 µg, 100 µg

Anti-Telethonin TCAP Antibody

WesternBlot (WB) analysis of TCAP polyclonal antibody

Human, Mouse, Rat

IF, WB

$405
Cat # A03590
100ul

TCAP Overview

Facts about Telethonin.

TCAP 3D structure. Source: alphafold

Telethonin (TCAP)

Muscle assembly regulating variable. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk.

Gene Information

Human
Gene Name:	TCAP
Uniprot:	O15273
Entrez:	8557

Family

Belongs to:

No superfamily

Alternative Names

19 kDa sarcomeric protein; CMD1NTitin cap protein; LGMD2G; limb girdle muscular dystrophy 2G (autosomal recessive); T-cap; TELE; telethonin; titin-cap (telethonin)

Molecular Weight

Mass (kDA):
19.052 kDA

Genomic Context


Human

Location:	17q12
Sequence:	17; NC_000017.11 (39665349..39666554)

Tissue Specificity

Heart and skeletal muscle.

Subcellular Localizations

Cytoplasm, myofibril, sarcomere.

Diseases

Cardiomyopathies
Muscular Dystrophy
Dystrophy
Muscular Dystrophies, Limb-girdle
Hypertrophy
Cardiomyopathy, Dilated
Malignant Neoplasms
Hypertrophic Cardiomyopathy
Cardiomyopathy, Familial Idiopathic
Myopathy
Heart Failure
Weakness
Neoplasms

Prostatic Neoplasms
Malignant Neoplasm Of Prostate
Anxiety Disorders
Muscular Atrophy
Atrophy
Cardiac Hypertrophy
Muscular Dystrophy, Duchenne

Interacting Proteins

CSRP3
MYOZ2
TTC19
TTN

Pathways

Localization
Pathogenesis
Cell Proliferation
Secretion
Sensitization
Translation
Muscle Atrophy
Startle Response
Rna Interference
Transport
Myoblast Proliferation
Muscle Cell Differentiation
Striated Muscle Hypertrophy

Regulation Of Gene Expression
Cardiac Conduction
Swimming
Cell Differentiation
Estrogen Secretion
Myoblast Differentiation
Somitogenesis

PTMs

Phosphorylation
Cleavage

Amidation
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TCAP

References

PMID: 9350988 by Valle G., et al. Telethonin, a novel sarcomeric protein of heart and skeletal muscle.

PMID: 9645487 by Mues A., et al. Two immunoglobulin-like domains of the Z-disc portion of titin interact in a conformation-dependent way with telethonin.