Tdrd12 Antibodies

AND Tdrd12 ELISA kits, Tdrd12 Proteins

Many biological assays use antibodies to detect Tdrd12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tdrd12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tdrd12 antibodies...

We validate the specificity of these antibodies to Tdrd12 by testing them on tissues known to express Tdrd12 positively and negatively. Browse below to find the Tdrd12 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Tdrd12 Infographic by Boster Bio

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TDRD12 (NM_001110822) Human Over-expression Lysate

Human

$628
Cat # LS091646
20 µg, 100 µg

Tdrd12 Overview

Facts about Putative ATP-dependent RNA helicase TDRD12.

Putative ATP-dependent RNA helicase TDRD12 (Tdrd12)

Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is vital for the germline integrity. Acts through the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and modulates the methylation and subsequent repression of transposons (PubMed:24067652).

Involved in the secondary piRNAs metabolic process (PubMed:24067652). Acts through the PET complex, a multiprotein complex required through the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs (PubMed:26669262).

Gene Information

Mouse
Gene Name:	Tdrd12
Uniprot:	Q9CWU0
Entrez:	71981

Family

Belongs to:

No superfamily

Alternative Names

Putative ATP-dependent RNA helicase TDRD12

Molecular Weight

Mass (kDA):
137.627 kDA

Genomic Context


Mouse

Location:	7\|7 B2
Sequence:	7;

Tissue Specificity

Restricted to the gonads.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Tdrd12

References

PMID: 12787504 by Mitsui K., et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells.

PMID: 24067652 by Pandey R.R., et al. Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice.