TDRD5 Antibodies

AND TDRD5 ELISA kits, TDRD5 Proteins

Many biological assays use antibodies to detect TDRD5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TDRD5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TDRD5 antibodies...

We validate the specificity of these antibodies to TDRD5 by testing them on tissues known to express TDRD5 positively and negatively. Browse below to find the TDRD5 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TDRD5 Infographic by Boster Bio

All TDRD5 Products

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Anti-TDRD5 Antibody Picoband®

Western blot analysis of TDRD5 using anti-TDRD5 antibody (A13514)

Flow Cytometry analysis of MCF-7 cells using anti-TDRD5 antibody (A13514)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A13514
100 μg/vial

TDRD5 Overview

Facts about Tudor domain-containing protein 5.

TDRD5 3D structure. Source: alphafold

Tudor domain-containing protein 5 (TDRD5)

Required during spermiogenesis to take part in the repression transposable elements and stop their mobilization, which is vital for the germline integrity. Probably acts through the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and regulate the methylation and subsequent repression of transposons.

Required for chromatoid body (CB) assembly (By similarity). .

Gene Information

Human
Gene Name:	TDRD5
Uniprot:	Q8NAT2
Entrez:	163589

Family

Belongs to:

TDRD5 family

Alternative Names

FLJ34823; RP11-427G13.1; tudor domain containing 5; tudor domain-containing protein 5; TUDOR3

Molecular Weight

Mass (kDA):
109.737 kDA

Genomic Context


Human

Location:	1q25.2
Sequence:	1; NC_000001.11 (179591613..179691272)

Subcellular Localizations

Cytoplasm. Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis.

Diseases

Cholangiocarcinoma
Virus Diseases
Malignant Neoplasms
Neoplasms
Liver Carcinoma
Hepatitis
Simian B Disease
Liver Neoplasms
Hepatitis B

Malignant Neoplasm Of Liver
Infertility
Carcinoma

Pathways

Cell Development
Localization
Germ Cell Development
Gastrulation
Fertilization
Aging
Spermatogenesis
Regulation Of Meiosis
Translation

Prophase
Hatching
Rna Processing
Meiosis

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TDRD5

References

PMID: 20302647 by Anantharaman V., et al. OST-HTH: a novel predicted RNA-binding domain.

PMID: 20305267 by Callebaut I., et al. LOTUS, a new domain associated with small RNA pathways in the germline.