TEX19 Antibodies

AND TEX19 ELISA kits, TEX19 Proteins

Many biological assays use antibodies to detect TEX19, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TEX19 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TEX19 antibodies...

We validate the specificity of these antibodies to TEX19 by testing them on tissues known to express TEX19 positively and negatively. Browse below to find the TEX19 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TEX19 Infographic by Boster Bio

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TEX19 Overview

Facts about Testis-expressed protein 19.

TEX19 3D structure. Source: alphafold

Testis-expressed protein 19 (TEX19)

Required during spermatogenesis and placenta development, participating in the repression of retrotransposable elements and stop their mobilization. Collaborates with the Piwi-interacting RNA (piRNA) pathway, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins.

Interacts with Piwi proteins and directly contrasts piRNAs, a class of 24 to 30 nucleotide RNAs which are made by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Also during spermatogenesis, promotes, with UBR2, SPO11-dependent recombination foci to accumulate and drive robust homologous chromosome synapsis (By similarity).

Gene Information

Human
Gene Name:	TEX19
Uniprot:	Q8NA77
Entrez:	400629

Family

Belongs to:

No superfamily

Alternative Names

FLJ35767; testis expressed 19; testis-expressed sequence 19 protein; TEX19

Molecular Weight

Mass (kDA):
18.469 kDA

Genomic Context


Human

Location:	17q25.3
Sequence:	17; NC_000017.11 (82359247..82363776)

Tissue Specificity

Expressed in testis. Expressed in undifferentiated embryonic stem cells.

Subcellular Localizations

Cytoplasm. Was initially reported to localize in the nucleus. However, it was later shown to localize in cytoplasm only. Cytoplasmic localization is distinct from the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis.

Pathways

Spermatogenesis
Transposition
Germ Cell Development
Translation
Cell Development
Cell Differentiation

Meiosis

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TEX19

References

PMID: 18096721 by Kuntz S., et al. Tex19, a mammalian-specific protein with a restricted expression in pluripotent stem cells and germ line.

PMID: 18160741 by Bayne R.A., et al. Molecular profiling of the human testis reveals stringent pathway- specific regulation of RNA expression following gonadotropin suppression and progestogen treatment.