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- Table of Contents
TGF-beta receptor type-1 Antibodies
AND TGFBR1 ELISA kits, TGF-beta receptor type-1 Proteins
Many biological assays use antibodies to detect TGF-beta receptor type-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TGF-beta receptor type-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TGF-beta receptor type-1 antibodies...
Designing a Western blot for TGF-beta receptor type-1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TGFBR1 Western Blot GuideTGFBR1 Infographic by Boster Bio
All TGFBR1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
WB
$370
Cat # PB10101
100 μg/vial
Cat # PB10101
100 μg/vial
Human
ELISA, WB
$370
Cat # A00832
100 μg/vial
Cat # A00832
100 μg/vial
Human
$960
Cat # LS007046
20 µg, 100 µg
Cat # LS007046
20 µg, 100 µg
TGFBR1 Overview
Facts about TGF-beta receptor type-1.
TGF-beta receptor type-1 (TGFBR1)
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Gene Information
| Human | |
|---|---|
| Gene Name: | TGFBR1 |
| Uniprot: | P36897 |
| Entrez: | 7046 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
AAT5; activin A receptor type II-like kinase, 53kD; activin A receptor type II-like kinase, 53kDa; Activin receptor-like kinase 5; ACVRLK4; ALK-5; ALK-5ALK5; EC 2.7.11; EC 2.7.11.30; LDS1A; LDS2A; Serine/threonine-protein kinase receptor R4; SKR4; tbetaR-I; TGFB1R1; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta RI; TGF-beta type I receptor; TGFbetaRI; TGFBR1; TGF-bRI; TGFR-1; transforming growth factor beta receptor I; transforming growth factor, beta receptor 1; transforming growth factor, beta receptor I (activin A receptor type II-likekinase, 53kD); Transforming growth factor
Molecular Weight
Mass (kDA):
55.96 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q22.33 |
| Sequence: | 9; NC_000009.12 (99104038..99154192) |
Tissue Specificity
Found in all tissues examined, most abundant in placenta and least abundant in brain and heart. Expressed in a variety of cancer cell lines (PubMed:25893292).
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Cell surface. Membrane raft.
Diseases
- Malignant Neoplasms
- Neoplasms
- Marfan Syndrome
- Aneurysm
- Loeys-dietz Syndrome
- Aortic Aneurysm
- Aortic Aneurysm, Thoracic
- Colorectal Cancer
- Carcinoma
- Connective Tissue Diseases
- Cleft Palate
- Colorectal Neoplasms
- Malignant Neoplasm Of Breast
Interacting Proteins
- FKBP1A
- LRG1
- TGFB1
- YWHAZ
Pathways
- Pathogenesis
- Cell Proliferation
- Secretion
- Localization
- Cell Growth
- Methylation
- Ovulation
- Cell Cycle
- Angiogenesis
- Cell Migration
- Oncogenesis
- Dna Methylation
- Regeneration
PTMs
- Phosphorylation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TGFBR1
bosterbio.com/bosterbio-gene-info-cards/TGFBR1
References
PMID: 8242743 by Franzen P., et al. Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor.
PMID: 9417915 by Vellucci V.F., et al. Cloning and genomic organization of the human transforming growth factor-beta type I receptor gene.
3 Publications of Boster TGF-beta receptor type-1 Antibodies & ELISA Kits
- PubMed ID: 26279755, Different localization and expression of protein kinase C-beta in kidney cortex ...
- PubMed ID: 21464546, Effects of interferon-alpha on expression of hepatic stellate cell and transform...
- PubMed ID: 11780431, Effects of AT1 receptor antagonist, losartan, on rat hepatic fibrosis induced by...
*More publications can be found for each product on its corresponding product page