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- Table of Contents
TGF-beta receptor type-1 Antibodies
AND TGFBR1 ELISA kits, TGF-beta receptor type-1 Proteins
Many biological assays use antibodies to detect TGF-beta receptor type-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TGF-beta receptor type-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TGF-beta receptor type-1 antibodies...
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TGFBR1 Infographic by Boster Bio
All TGFBR1 Products
Product
Figures
Specificity
Applications
Price
Anti-TGF beta Receptor I/TGFBR1 Antibody Picoband®
1 Citations 1 Q&As
Human
WB
$370
Cat # PB9828
100 μg/vial
Cat # PB9828
100 μg/vial
Human, Mouse, Rat
WB
$370
Cat # PB10101
100 μg/vial
Cat # PB10101
100 μg/vial
Human
ELISA, WB
$370
Cat # A00832
100 μg/vial
Cat # A00832
100 μg/vial
Human
$960
Cat # LS007046
20 µg, 100 µg
Cat # LS007046
20 µg, 100 µg
TGFBR1 Overview
Facts about TGF-beta receptor type-1.
TGF-beta receptor type-1 (TGFBR1)
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Gene Information
| Human | |
|---|---|
| Gene Name: | TGFBR1 |
| Uniprot: | P36897 |
| Entrez: | 7046 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
AAT5; activin A receptor type II-like kinase, 53kD; activin A receptor type II-like kinase, 53kDa; Activin receptor-like kinase 5; ACVRLK4; ALK-5; ALK-5ALK5; EC 2.7.11; EC 2.7.11.30; LDS1A; LDS2A; Serine/threonine-protein kinase receptor R4; SKR4; tbetaR-I; TGFB1R1; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta RI; TGF-beta type I receptor; TGFbetaRI; TGFBR1; TGF-bRI; TGFR-1; transforming growth factor beta receptor I; transforming growth factor, beta receptor 1; transforming growth factor, beta receptor I (activin A receptor type II-likekinase, 53kD); Transforming growth factor
Molecular Weight
Mass (kDA):
55.96 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q22.33 |
| Sequence: | 9; NC_000009.12 (99104038..99154192) |
Tissue Specificity
Found in all tissues examined, most abundant in placenta and least abundant in brain and heart. Expressed in a variety of cancer cell lines (PubMed:25893292).
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Cell surface. Membrane raft.
Diseases
- Malignant Neoplasms
- Neoplasms
- Marfan Syndrome
- Aneurysm
- Loeys-dietz Syndrome
- Aortic Aneurysm
- Aortic Aneurysm, Thoracic
- Colorectal Cancer
- Carcinoma
- Connective Tissue Diseases
- Cleft Palate
- Colorectal Neoplasms
- Malignant Neoplasm Of Breast
Interacting Proteins
- FKBP1A
- LRG1
- TGFB1
- YWHAZ
Pathways
- Pathogenesis
- Cell Proliferation
- Secretion
- Localization
- Cell Growth
- Methylation
- Ovulation
- Cell Cycle
- Angiogenesis
- Cell Migration
- Oncogenesis
- Dna Methylation
- Regeneration
PTMs
- Phosphorylation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TGFBR1
bosterbio.com/bosterbio-gene-info-cards/TGFBR1
References
PMID: 8242743 by Franzen P., et al. Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor.
PMID: 9417915 by Vellucci V.F., et al. Cloning and genomic organization of the human transforming growth factor-beta type I receptor gene.
3 Publications of Boster TGF-beta receptor type-1 Antibodies & ELISA Kits
- PubMed ID: 26279755, Different localization and expression of protein kinase C-beta in kidney cortex ...
- PubMed ID: 21464546, Effects of interferon-alpha on expression of hepatic stellate cell and transform...
- PubMed ID: 11780431, Effects of AT1 receptor antagonist, losartan, on rat hepatic fibrosis induced by...
*More publications can be found for each product on its corresponding product page