TIE1 Antibodies

AND TIE1 ELISA kits, TIE1 Proteins

Many biological assays use antibodies to detect TIE1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TIE1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TIE1 antibodies...

We validate the specificity of these antibodies to TIE1 by testing them on tissues known to express TIE1 positively and negatively. Browse below to find the TIE1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TIE1 Infographic by Boster Bio

All TIE1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

TIE1 (NM_005424) Human Recombinant Protein

$1296
Cat # PROTP35590
20 µg

TIE1 (NM_005424) Human Over-expression Lysate

Human

$628
Cat # LS007075
20 µg, 100 µg

Anti-Zebrafish TIE1 Antibody Picoband®

Western blot analysis of TIE1 using anti-TIE1 antibody (AZG1K2H0)

Zebrafish

$470
Cat # AZG1K2H0
100 μg/vial

TIE1 Overview

Facts about Tyrosine-protein kinase receptor Tie-1.

TIE1 3D structure. Source: alphafold

Tyrosine-protein kinase receptor Tie-1 (TIE1)

Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 action and contribute to the regulation of angiogenesis. .

Gene Information

Human
Gene Name:	TIE1
Uniprot:	P35590
Entrez:	7075

Family

Belongs to:

protein kinase superfamily

Alternative Names

EC 2.7.10; EC 2.7.10.1; JTK14soluble TIE1 variant 3; receptor tyrosine kinase; soluble TIE1 variant 1; soluble TIE1 variant 2; soluble TIE1 variant 5; Tie1; Tie-1; TIEsoluble TIE1 variant 4; tyrosine kinase with immunoglobulin and epidermal growth factor homologydomains 1; tyrosine kinase with immunoglobulin-like and EGF-like domains 1; tyrosine-protein kinase receptor Tie-1

Molecular Weight

Mass (kDA):
125.09 kDA

Genomic Context


Human

Location:	1p34.2
Sequence:	1; NC_000001.11 (43300954..43323108)

Tissue Specificity

Specifically expressed in developing vascular endothelial cells.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Tumor Angiogenesis
Neoplasms
Pathologic Neovascularization
Malignant Neoplasms
Tissue Adhesions
Multiple Endocrine Neoplasia Type 1
Hypoxia
Hemorrhage
Neoplasm Metastasis
Malignant Paraganglionic Neoplasm
Carcinoma
Inflammation

Edema
Sarcoma
Arthritis
Mammary Neoplasms
Ischemia
Diabetes Mellitus
Neoplasms, Experimental

Interacting Proteins

KRT40
PSG5
RBPMS

Pathways

Angiogenesis
Lymphangiogenesis
Cell Adhesion
Cell Proliferation
Secretion
Vasculogenesis
Pathogenesis
Regulation Of Angiogenesis
Reverse Transcription
Wound Healing
Blood Vessel Development
Cell Development
Blood Vessel Morphogenesis

Localization
Cell Differentiation
Glycosylation
Regeneration
Heart Development
Response To Hypoxia
Cell Growth

PTMs

Phosphorylation
Cleavage

Glycosylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TIE1

References

PMID: 1312667 by Partanen J., et al. A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains.

PMID: 18593464 by Jin P., et al. Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.