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- Table of Contents
TIMP3 Antibodies
AND TIMP3 ELISA kits, TIMP3 Proteins
Many biological assays use antibodies to detect TIMP3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TIMP3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TIMP3 antibodies...
Designing a Western blot for TIMP3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TIMP3 Western Blot GuideTIMP3 Infographic by Boster Bio
All TIMP3 Products
Product
Figures
Specificity
Applications
Price
Human TIMP-3 ELISA Kit PicoKine®
4 Citations
Human
ELISA
$499
Cat # EK0523
96 wells/kit, with removable strips.
Cat # EK0523
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK0523
96 wells/kit, with removable strips.
Cat # FEK0523
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, WB
$370
Cat # PA1077
100 μg/vial
Cat # PA1077
100 μg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1565
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1565
1 kit, containing one 96-well plate and all necessary reagents
Monkey
ELISA
$499
Cat # EK0523-PR
96 wells/kit, with removable strips.
Cat # EK0523-PR
96 wells/kit, with removable strips.
Pig
ELISA
$499
Cat # EK0523-PO
96 wells/kit, with removable strips.
Cat # EK0523-PO
96 wells/kit, with removable strips.
Equine
ELISA
$499
Cat # EK0523-EQ
96 wells/kit, with removable strips.
Cat # EK0523-EQ
96 wells/kit, with removable strips.
TIMP3 Overview
Facts about Metalloproteinase inhibitor 3.
Metalloproteinase inhibitor 3 (TIMP3)
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute reaction to remodeling stimuli.
Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TIMP3 |
| Uniprot: | P35625 |
| Entrez: | 7078 |
Family
| Belongs to: |
|---|
| protease inhibitor I35 (TIMP) family |
Alternative Names
HSMRK222; K222; K222TA2; metalloproteinase inhibitor 3; MIG-5 protein; Protein MIG-5; pseudoinflammatory); SFD; TIMP metallopeptidase inhibitor 3; TIMP3; TIMP-3; tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy; Tissue inhibitor of metalloproteinases 3
Molecular Weight
Mass (kDA):
24.145 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q12.3 |
| Sequence: | 22; NC_000022.11 (32801705..32863041) |
Subcellular Localizations
Secreted, extracellular space, extracellular matrix.
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Age Related Macular Degeneration
- Cell Invasion
- Neoplasm Metastasis
- Dystrophy
- Inflammation
- Sorsby's Fundus Dystrophy
- Malignant Neoplasm Of Breast
- Adenocarcinoma
- Carcinogenesis
- Cell Transformation, Neoplastic
Interacting Proteins
- AGTR2
Pathways
- Methylation
- Pathogenesis
- Dna Methylation
- Angiogenesis
- Gene Silencing
- Cell Proliferation
- Localization
- Cell Adhesion
- Cell Cycle
- Wound Healing
- Proteolysis
- Dna Hypermethylation
- Cell Growth
PTMs
- Methylation
- Cleavage
- Demethylation
- Phosphorylation
- Glycosylation
Research Areas
- Angiogenesis
- Apoptosis
- Cancer
- Hypoxia
- Metastasis
- Vision
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TIMP3
bosterbio.com/bosterbio-gene-info-cards/TIMP3
References
PMID: 8174111 by Uria J.A., et al. Structure and expression in breast tumors of human TIMP-3, a new member of the metalloproteinase inhibitor family.
PMID: 7772252 by Wilde C.G., et al. Cloning and characterization of human tissue inhibitor of metalloproteinases-3.
6 Publications of Boster TIMP3 Antibodies & ELISA Kits
- PubMed ID: 10.3390/cancers11111687, Fibroblasts in Nodular Sclerosing Classical Hodgkin Lymphoma Are Defined by a Sp...
- PubMed ID: 10.1155/2017/9542702, Paracrine Potential of the Human Adipose Tissue-Derived Stem Cells to Modulate B...
- PubMed ID: 33649809, Nie L,Liu M,Chen J,Wu Q,Li Y,Yi J,Zheng X,Zhang J,Chu C,Yang J.Hydrogen sulfide ...
- PubMed ID: 23819566, Promoter methylation and expression of TIMP3 gene in gastric cancer
- PubMed ID: 28819366, Denkovskij, J., Bagdonas, E., Kusleviciute, I., Mackiewicz, Z., Unguryte, A., Po...
- PubMed ID: 17657847, Bai Yx, Yi Jl, Li Jf, Sui H. World J Gastroenterol. 2007 Jul 28;13(28):3883-5. C...
*More publications can be found for each product on its corresponding product page