Transmembrane protein 108 Antibodies

AND TMEM108 ELISA kits, Transmembrane protein 108 Proteins

Many biological assays use antibodies to detect Transmembrane protein 108, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transmembrane protein 108 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transmembrane protein 108 antibodies...

We validate the specificity of these antibodies to Transmembrane protein 108 by testing them on tissues known to express TMEM108 positively and negatively. Browse below to find the TMEM108 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TMEM108 Infographic by Boster Bio

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TMEM108 Overview

Facts about Transmembrane protein 108.

TMEM108 3D structure. Source: alphafold

Transmembrane protein 108 (TMEM108)

Transmembrane protein required for proper cognitive functions. Involved in the development of dentate gyrus (DG) neuron circuitry, is neccessary for AMPA receptors surface expression and appropriate excitatory postsynaptic currents of DG granule neurons.

Regulates the organization and stability of the microtubule network of sensory nerves to allow axonal transport. Through the interaction with DST, mediates the docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport.

Gene Information

Human
Gene Name:	TMEM108
Uniprot:	Q6UXF1
Entrez:	66000

Family

Belongs to:

No superfamily

Alternative Names

Transmembrane protein 108

Molecular Weight

Mass (kDA):
59.948 kDA

Genomic Context


Human

Location:	3q22.1
Sequence:	3; NC_000003.12 (133038288..133397775)

Subcellular Localizations

Membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic density. Endosome membrane. Cell projection, axon. Cell projection, dendrite. Early endosome.

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TMEM108

References

PMID: 12975309 by Clark H.F., et al. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PMID: 11214970 by Nagase T., et al. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.