Transmembrane protein 127 Antibodies

AND TMEM127 ELISA kits, Transmembrane protein 127 Proteins

Many biological assays use antibodies to detect Transmembrane protein 127, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transmembrane protein 127 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transmembrane protein 127 antibodies...

We validate the specificity of these antibodies to Transmembrane protein 127 by testing them on tissues known to express TMEM127 positively and negatively. Browse below to find the TMEM127 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TMEM127 Infographic by Boster Bio

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TMEM127 (NM_017849) Human Over-expression Lysate

Human

$628
Cat # LS055654
20 µg, 100 µg

TMEM127 Overview

Facts about Transmembrane protein 127.

TMEM127 3D structure. Source: alphafold

Transmembrane protein 127 (TMEM127)

Controls cell proliferation acting as a negative regulator of TOR signaling pathway mediated by mTORC1. May act as a tumor suppressor.

Gene Information

Human
Gene Name:	TMEM127
Uniprot:	O75204
Entrez:	55654

Family

Belongs to:

TMEM127 family

Alternative Names

Transmembrane protein 127

Molecular Weight

Mass (kDA):
25.842 kDA

Genomic Context


Human

Location:	2q11.2
Sequence:	2; NC_000002.12 (96248514..96265997, complement)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cytoplasm. Association of TMEM127 with the cell membrane is enhanced by inhibition of endocytosis. In the cytoplasm, it colocalizes with markers of early endosomal structures, Golgi apparatus and lysosomes.

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TMEM127

References

PMID: 20154675 by Qin Y., et al. Germline mutations in TMEM127 confer susceptibility to pheochromocytoma.

PMID: 25732826 by Aksnes H., et al. An organellar nalpha-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity.