TMEM150B Antibodies

AND TMEM150B ELISA kits, TMEM150B Proteins

Many biological assays use antibodies to detect TMEM150B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TMEM150B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TMEM150B antibodies...

We validate the specificity of these antibodies to TMEM150B by testing them on tissues known to express TMEM150B positively and negatively. Browse below to find the TMEM150B antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: MBD3L5

TMEM150B Infographic by Boster Bio

All TMEM150B Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

TMEM150B Overview

Facts about Modulator of macroautophagy TMEM150B.

TMEM150B 3D structure. Source: alphafold

Modulator of macroautophagy TMEM150B (TMEM150B)

Modulator of macroautophagy that causes accumulation of autophagosomes under basal conditions and enhances autophagic flux (PubMed:25929859). Represses cell death and promotes long-term clonogenic survival of cells grown in the absence of glucose in a macroautophagy-independent manner (PubMed:25929859).

May have some role in extracellular matrix engulfment or growth factor receptor recycling, both of which can modulate cell survival (PubMed:25929859). .

Gene Information

Human
Gene Name:	TMEM150B
Uniprot:	A6NC51
Entrez:	284417

Family

Belongs to:

DRAM/TMEM150 family

Alternative Names

Modulator of macroautophagy TMEM150B

Molecular Weight

Mass (kDA):
25.701 kDA

Genomic Context


Human

Location:	19q13.42
Sequence:	19; NC_000019.10 (55308869..55334043, complement)

Tissue Specificity

Highly expressed in the colon and lung with comparatively high levels also detectable in the lymph nodes, placenta, duodenum, peripheral blood mononuclear cells and spleen (PubMed:25929859).

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Localizes mainly at the plasma membrane where it concentrates at actin-rich focal adhesions (PubMed:25608530, PubMed:25929859).

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TMEM150B

References

PMID: 25608530 by Chung J., et al. Plasticity of PI4KIIIalpha interactions at the plasma membrane.

PMID: 25929859 by Mrschtik M., et al. DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose.