Transmembrane protein 33 Antibodies

AND TMEM33 ELISA kits, Transmembrane protein 33 Proteins

Many biological assays use antibodies to detect Transmembrane protein 33, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transmembrane protein 33 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transmembrane protein 33 antibodies...

We validate the specificity of these antibodies to Transmembrane protein 33 by testing them on tissues known to express TMEM33 positively and negatively. Browse below to find the TMEM33 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TMEM33 Infographic by Boster Bio

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TMEM33 (NM_018126) Human Over-expression Lysate

Human

$628
Cat # LS055161
20 µg, 100 µg

TMEM33 Overview

Facts about Transmembrane protein 33.

TMEM33 3D structure. Source: alphafold

Transmembrane protein 33 (TMEM33)

Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules (PubMed:25612671).

Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling (PubMed:26268696). .

Gene Information

Human
Gene Name:	TMEM33
Uniprot:	P57088
Entrez:	55161

Family

Belongs to:

PER33/POM33 family

Alternative Names

DB83; FLJ10525; Protein DB83; SHINC3,1600019D15Rik; transmembrane protein 33

Molecular Weight

Mass (kDA):
27.978 kDA

Genomic Context


Human

Location:	4p13
Sequence:	4; NC_000004.12 (41935120..41960803)

Tissue Specificity

Prostate cancer and several cancer cell lines (at protein level). Widely expressed. Expressed at higher levels in endocrine-resistant breast cancer cells as compared to endocrine-sensitive breast cancer cells. Expressed at higher levels in early recurrence breast cancer tissues as compared to non-recurrent breast tumors.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. Melanosome. Nucleus envelope. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Co-localizes with RTN4 at the ER sheets.

Interacting Proteins

MTNR1A

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TMEM33

References

PMID: 25612671 by Urade T., et al. Identification and characterization of TMEM33 as a reticulon-binding protein.

PMID: 26268696 by Sakabe I., et al. TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling.