TMEM59L Antibodies

AND TMEM59L ELISA kits, TMEM59L Proteins

Many biological assays use antibodies to detect TMEM59L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TMEM59L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TMEM59L antibodies...

We validate the specificity of these antibodies to TMEM59L by testing them on tissues known to express TMEM59L positively and negatively. Browse below to find the TMEM59L antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TMEM59L Infographic by Boster Bio

All TMEM59L Products

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Applications

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Anti-Transmembrane protein 59-like TMEM59L Antibody

Western blot analysis of TMEM59L in rat heart tissue lysate with TMEM59L antibody at 1 μg/mL

Immunohistochemistry of TMEM59L in mouse brain tissue with TMEM59L antibody at 2

Immunofluorescence of TMEM59L in mouse brain tissue with TMEM59L antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A15285
0.1 mg

TMEM59L (NM_012109) Human Over-expression Lysate

Human

$628
Cat # LS025789
20 µg, 100 µg

TMEM59L Overview

Facts about Transmembrane protein 59-like.

TMEM59L 3D structure. Source: alphafold

Transmembrane protein 59-like (TMEM59L)

Modulates the O-glycosylation and complex N- glycosylation steps occurring Throughout the Golgi maturation of APP.
Inhibits APP transfer to the cell surface and further shedding.

Gene Information

Human
Gene Name:	TMEM59L
Uniprot:	Q9UK28
Entrez:	25789

Family

Belongs to:

TMEM59 family

Alternative Names

BSMAPBrain-specific membrane-anchored protein; C19orf4; chromosome 19 open reading frame 4; transmembrane protein 59-like

Molecular Weight

Mass (kDA):
37.619 kDA

Genomic Context


Human

Location:	19p13.11
Sequence:	19; NC_000019.10 (18612870..18621040)

Tissue Specificity

Expressed preferentially at high level in the brain.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type I membrane protein.

Diseases

Alzheimer's Disease
Hereditary Diseases

Pathways

Methylation
Dna Methylation
Glycosylation
Pathogenesis
Localization
Secretion

PTMs

Glycosylation

Cleavage

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TMEM59L

References

PMID: 10527841 by Elson G.C.A., et al. BSMAP, a novel protein expressed specifically in the brain whose gene is localized on chromosome 19p12.

PMID: 20427278 by Ullrich S., et al. The novel membrane protein TMEM59 modulates complex glycosylation, cell surface expression, and secretion of the amyloid precursor protein.