Tmub1 Antibodies

AND Tmub1 ELISA kits, Tmub1 Proteins

Many biological assays use antibodies to detect Tmub1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tmub1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tmub1 antibodies...

We validate the specificity of these antibodies to Tmub1 by testing them on tissues known to express Tmub1 positively and negatively. Browse below to find the Tmub1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Tmub1 Infographic by Boster Bio

All Tmub1 Products

Product

Figures

Specificity

Applications

Price

TMUB1 (NM_001136044) Human Recombinant Protein

$1249
Cat # PROTQ9BVT8
20 µg

TMUB1 (NM_031434) Human Over-expression Lysate

Human

$628
Cat # LS083590
100 µg

Tmub1 Overview

Facts about Transmembrane and ubiquitin-like domain-containing protein 1.

Transmembrane and ubiquitin-like domain-containing protein 1 (Tmub1)

Involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR (By similarity). Involved in positive regulation of AMPA-selective glutamate receptor GRIA2 recycling to the cell surface (By similarity).

Acts as negative regulator of hepatocyte growth during regeneration (By similarity). .

Gene Information

Mouse
Gene Name:	Tmub1
Uniprot:	Q9JMG3
Entrez:	64295

Family

Belongs to:

No superfamily

Alternative Names

C7orf21; chromosome 7 open reading frame 21; DULP; Hepatocyte odd protein shuttling protein; HOPS; MGC5442; SB144; transmembrane and ubiquitin-like domain containing 1; transmembrane and ubiquitin-like domain-containing protein 1; Ubiquitin-like protein DULP; Ubiquitin-like protein SB144

Molecular Weight

Mass (kDA):
26.316 kDA

Genomic Context


Mouse

Location:	5\|5 A3
Sequence:	5;

Tissue Specificity

Expressed in adult brain; at protein level (PubMed:18665261, PubMed:20582322). Isoform 1 (lHOPS) is highly expressed in small intestine, stomach and epididymis. Isoform 2 (sHOPS) and iHOPS are abundantly expressed in brain, liver and adrenal gland (PubMed:24240191).

Diseases

Nervousness
Lentivirus Infections
Liver Regeneration Disorder

Pathways

Regeneration
Cell Proliferation
Liver Regeneration
Synaptic Transmission
Rna Interference
Hepatocyte Proliferation

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Tmub1

References

PMID: 10679242 by Inoue S., et al. Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains.

PMID: 16014383 by Della Fazia M.A., et al. HOPS: a novel cAMP-dependent shuttling protein involved in protein synthesis regulation.