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Receptor for TNFSF18.Appears to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death.
Mediated NF-kappa-B activation through the TRAF2/NIK pathway. .
|Sequence:||1; NC_000001.11 (1203508..1207901, complement)|
Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.