TNFSF9 Antibodies

AND TNFSF9 ELISA kits, TNFSF9 Proteins

Many biological assays use antibodies to detect TNFSF9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNFSF9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNFSF9 antibodies...

We validate the specificity of these antibodies to TNFSF9 by testing them on tissues known to express TNFSF9 positively and negatively. Browse below to find the TNFSF9 antibody that suites your experiment. We have 9 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TNFSF9 Infographic by Boster Bio

All TNFSF9 Products

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Product

Figures

Specificity

Applications

Price

TNFSF9 Colorimetric Cell-Based ELISA

Western blot analysis of extracts from HuvEc cells

Human

ELISA

$480
Cat # EKC1721
1 kit, containing one 96-well plate and all necessary reagents

TNFSF9 (NM_003811) Human Recombinant Protein

$1296
Cat # PROTP41273
20 µg

Anti-TNFSF9 Mouse Monoclonal Antibody [Clone ID: OTI3B6]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CD137L (Right lane) cDNA for 48 hrs and lysed

Flow cytometric analysis of living Raji cells

Flow cytometric analysis of living 293T cells transfected with CD137L overexpression plasmid

Human

Flow Cytometry, WB

$523
Cat # M06032
100 µl

Anti-TNFSF9 Rabbit Monoclonal Antibody

Western blot analysis of TNFSF9 expression in HEK293 cell lysate

Human

IP, WB

$370
Cat # M06032-1
100 μl/vial

TNFSF9 (NM_003811) Human Over-expression Lysate

Human

$628
Cat # LS008744
20 µg, 100 µg

Anti-4-1BBL/Tnfsf9 Antibody Picoband®

Western blot analysis of 4-1BBL/Tnfsf9 using anti-4-1BBL/Tnfsf9 antibody (A06032-2)

Flow Cytometry analysis of ANA-1 cells using anti-4-1BBL/Tnfsf9 antibody (A06032-2)

Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A06032-2
100 μg/vial

Human recombinant 4-1BBL (4-1BB ligand) protein, AF

Human

Cell Culture

$77
Cat # PROTP41273-3
5ug,20ug,100ug

Mouse recombinant 4-1BBL (4-1BB ligand) protein, AF

Mouse

Cell Culture

$77
Cat # PROTP41274
5ug,20ug,100ug

Anti-TNFSF9 / 4-1BBL Reference Antibody (Abbvie patent anti-TNFSF9)

The purity of Anti-TNFSF9/4-1BBL Reference Antibody (Abbvie patent anti-TNFSF9)is more than 95%

Cynomolgus monkey, Human

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M06032-2
100 μg

TNFSF9 Overview

Facts about Tumor necrosis factor ligand superfamily member 9.

TNFSF9 3D structure. Source: alphafold

Tumor necrosis factor ligand superfamily member 9 (TNFSF9)

Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells.

May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

Gene Information

Human
Gene Name:	TNFSF9
Uniprot:	P41273
Entrez:	8744

Family

Belongs to:

tumor necrosis factor family

Alternative Names

41BB Ligand; 4-1BB Ligand; 4-1BBL; 4-1BB-L; CD137L; homolog of mouse 4-1BB-L; receptor 4-1BB ligand; TNFSF9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand superfamily member 9

Molecular Weight

Mass (kDA):
26.625 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (6531026..6535924)

Tissue Specificity

Expressed in brain, placenta, lung, skeletal muscle and kidney.

Subcellular Localizations

Membrane; Single-pass type II membrane protein.

Diseases

Neoplasms
Malignant Neoplasms
Carcinoma
Lymphoma
Inflammation
Autoimmune Reaction
Influenza
Autoimmune Diseases
B-cell Lymphomas
Colonic Neoplasms
Leukemia
Neoplasm Metastasis

Neoplasms, Experimental
Liver Carcinoma
Liver Neoplasms
Graft-vs-host Disease
Autoimmunity
Malignant Tumor Of Colon
Decreased Immunologic Activity [pe]

Pathways

Cell Activation
Immune Response
T Cell Activation
Cell Proliferation
Secretion
Cytokine Production
T Cell Proliferation
Cell Death
Pathogenesis
Cell Adhesion
Cell Division
Lymphocyte Proliferation
Humoral Immune Response

Drug Resistance
Germinal Center Formation
Cell Migration
Response To Peptide
Memory T Cell Activation
Cytokine Secretion
Proteolysis

PTMs

Phosphorylation

Biotinylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNFSF9

References

PMID: 8088337 by Alderson M.R., et al. Molecular and biological characterization of human 4-1BB and its ligand.

PMID: 20032458 by Won E.Y., et al. The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily.