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- Table of Contents
Facts about TNFAIP3-interacting protein 1.
Increases cell surface CD4(T4) antigen expression. Involved in the anti- inflammatory response of macrophages and positively regulates TLR- induced activation of CEBPB.
Human | |
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Gene Name: | TNIP1 |
Uniprot: | Q15025 |
Entrez: | 10318 |
Belongs to: |
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No superfamily |
ABIN-1; HIV-1 Nef-interacting protein; hVAN; KIAA0113nip40-1; Naf1; NAF1TNFAIP3-interacting protein 1; Nef-associated factor 1 SNP; Nef-associated factor 1; Nip40-1; TNFAIP3 interacting protein 1; VANvirion-associated nuclear-shuttling protein; Virion-associated nuclear shuttling protein
Mass (kDA):
71.864 kDA
Human | |
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Location: | 5q33.1 |
Sequence: | 5; NC_000005.10 (151029943..151087685, complement) |
Ubiquitous. Strongly expressed in peripheral blood lymphocytes, spleen and skeletal muscle, and is weakly expressed in the brain. In peripheral blood mononucleocytes, isoform 4 is mainly expressed and isoform 1 and isoform 7 are almost not expressed. Expression of isoform 1 and isoform 7 increases in leukemic cells.
Cytoplasm. Nucleus. Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner.
The TNIP1Marker has many uses. But how can you use it? This article will give you a brief history of Steven Boster, his background and what TNIP1 is and how you can use it. Steven Boster is an extremely influential person in the field of molecular biology. Moreover, he also has a fascinating bio.
Steven Boster's history is full of landmarks. Boster, an innovative biotech entrepreneur, began his first product development in 1993. Boster soon earned the nickname of "the man who converts science in the lavatory." His early success led to dozens of IHC products, hundreds of primary antibodies, and even his own patent. Boster's unique method of developing and manufacturing ELISA products led to his company being one of China's most recognized catalog antibody manufacturers.
Steve Boster died in Madison, WI, June 20, 2022. He was the only child of Evelyn Meier Boster and James Meier Boster. He was a manager for many years and was a member of Concordia Hall in Staunton. His family includes Crystal Boster and Natosha Peck, as well as six grandchildren, four brothers, Jack Blanton and Sandra Blanton, and his sister Tammy. His nieces & nephews also survived him.
TNIP1 can be associated with a number of human diseases including cancer. Boster first discovered the gene in 1993. It has been a key element in the treatment and prevention of inflammatory diseases. It has been implicated as a key factor in the development many types antibiotics, including penicillin. TNIP1 is also known to play a role in the production a variety other human proteins including insulin.
PMID: 9923610 by Fukushi M., et al. Identification and cloning of a novel cellular protein Naf1, Nef- associated factor 1, that increases cell surface CD4 expression.
PMID: 11090181 by Gupta K., et al. A human nuclear shuttling protein that interacts with human immunodeficiency virus type 1 matrix is packaged into virions.