This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
TNP1 Antibodies
AND TNP1 ELISA kits, TNP1 Proteins
Many biological assays use antibodies to detect TNP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNP1 antibodies...
Previous: CBLIF
Next: TNP2
TNP1 Infographic by Boster Bio
All TNP1 Products
Product
Figures
Specificity
Applications
Price
Human
$628
Cat # LS007141
20 µg, 100 µg
Cat # LS007141
20 µg, 100 µg
TNP1 Overview
Facts about Spermatid nuclear transition protein 1.
Spermatid nuclear transition protein 1 (TNP1)
Plays a crucial role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | TNP1 |
| Uniprot: | P09430 |
| Entrez: | 7141 |
Family
| Belongs to: |
|---|
| nuclear transition protein 1 family |
Alternative Names
spermatid nuclear transition protein 1; STP-1; TP1; TP-1; transition protein 1 (during histone to protamine replacement)
Molecular Weight
Mass (kDA):
6.424 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q35 |
| Sequence: | 2; NC_000002.12 (216859458..216860064, complement) |
Tissue Specificity
Expressed by spermatids (at protein level).
Subcellular Localizations
Nucleus. Chromosome. Loaded onto the nucleosomes of condensing spermatids.
Diseases
- Infertility
- Male Infertility
- Leprosy
- Leishmaniasis, Visceral
- Azoospermia
- Oligospermia
- Leishmaniasis
- Colonic Neoplasms
- Polyps
- Malignant Tumor Of Colon
- Spermatogenesis Abnormal
- Carcinogenesis
- Rheumatism
Interacting Proteins
- SDCBP2
Pathways
- Spermatogenesis
- Translation
- Localization
- Methylation
- Histone Displacement
- Fertilization
- Prophase
- Histone Lysine Methylation
- Sperm Motility
- Pachytene
- Transport
- Histone Modification
- Regulation Of Gene Expression
PTMs
- Methylation
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNP1
bosterbio.com/bosterbio-gene-info-cards/TNP1
References
PMID: 3412903 by Luerssen H., et al. The nucleotide sequence of human transition protein 1 cDNA.
PMID: 2249851 by Luerssen H., et al. Nucleotide sequence of the gene for human transition protein 1 and its chromosomal localization on chromosome 2.