TNRC6B Antibodies

AND TNRC6B ELISA kits, TNRC6B Proteins

Many biological assays use antibodies to detect TNRC6B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNRC6B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNRC6B antibodies...

We validate the specificity of these antibodies to TNRC6B by testing them on tissues known to express TNRC6B positively and negatively. Browse below to find the TNRC6B antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TNRC6B Infographic by Boster Bio

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TNRC6B (NM_001024843) Human Over-expression Lysate

Human

$628
Cat # LS023112
20 µg, 100 µg

TNRC6B Overview

Facts about Trinucleotide repeat-containing gene 6B protein.

TNRC6B 3D structure. Source: alphafold

Trinucleotide repeat-containing gene 6B protein (TNRC6B)

Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins.

As scaffoldng protein partners with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes. .

Gene Information

Human
Gene Name:	TNRC6B
Uniprot:	Q9UPQ9
Entrez:	23112

Family

Belongs to:

GW182 family

Alternative Names

KIAA1093trinucleotide repeat-containing gene 6B protein; trinucleotide repeat containing 6B

Molecular Weight

Mass (kDA):
194.002 kDA

Genomic Context


Human

Location:	22q13.1
Sequence:	22; NC_000022.11 (40044817..40335808)

Subcellular Localizations

Cytoplasm, P-body. Mammalian P-bodies are also known as GW bodies (GWBs).

Diseases

Malignant Neoplasm Of Prostate
Prostatic Neoplasms
Malignant Neoplasms
Immunologic Deficiency Syndromes
Embryonal Carcinoma
Nervousness

Interacting Proteins

AGO1
AGO2
CNOT1
PABPC1
PAN3

Pathways

Translation
Gene Silencing
Localization
Mrna Cleavage
Brain Development
Rna Interference
Pre-mirna Processing

Secretion

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNRC6B

References

PMID: 16289642 by Meister G., et al. Identification of novel argonaute-associated proteins.

PMID: 18690212 by Qi H.H., et al. Prolyl 4-hydroxylation regulates Argonaute 2 stability.