Tensin-4 Antibodies

AND TNS4 ELISA kits, Tensin-4 Proteins

Many biological assays use antibodies to detect Tensin-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tensin-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tensin-4 antibodies...

We validate the specificity of these antibodies to Tensin-4 by testing them on tissues known to express TNS4 positively and negatively. Browse below to find the TNS4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TNS4 Infographic by Boster Bio

All TNS4 Products

Product

Figures

Specificity

Applications

Price

Anti-TNS4 Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M07240
100 μl/vial

TNS4 (NM_032865) Human Over-expression Lysate

Human

$960
Cat # LS084951
100 µg

TNS4 Overview

Facts about Tensin-4.

TNS4 3D structure. Source: alphafold

Tensin-4 (TNS4)

May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity). May promote apoptosis, via its cleavage by caspase-3.

. .

Gene Information

Human
Gene Name:	TNS4
Uniprot:	Q8IZW8
Entrez:	84951

Family

Belongs to:

PTEN phosphatase protein family

Alternative Names

CTEN; CTENC terminal tensin like; C-terminal tensin-like protein; FLJ14950; Tensin 4; tensin-4; TNS4

Molecular Weight

Mass (kDA):
76.764 kDA

Genomic Context


Human

Location:	17q21.2
Sequence:	17; NC_000017.11 (40475828..40501681, complement)

Tissue Specificity

Prostate and placenta. Down regulated in prostate cancer.

Subcellular Localizations

Cell junction, focal adhesion. Cytoplasm, cytoskeleton.

Diseases

Malignant Neoplasms
Neoplasm Metastasis
Carcinoma
Neoplasms
Colorectal Cancer
Cell Invasion
Colorectal Neoplasms
Keratosis
Sclerosis
Stomach Neoplasms
Peritoneal Neoplasms
Metastatic Malignant Neoplasm To The Lymph Node

Malignant Neoplasm Of Breast
Seborrheic Keratosis
Pancreatic Neoplasm
Mammary Neoplasms
Malignant Neoplasm Of Pancreas
Adenocarcinoma
Neoplasm Recurrence, Local

Pathways

Cell Motility
Cell Migration
Pathogenesis
Localization

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNS4

References

PMID: 12154022 by Lo S.H., et al. Cten, a COOH-terminal tensin-like protein with prostate restricted expression, is down-regulated in prostate cancer.

PMID: 15806167 by Lo S.-S., et al. Cleavage of cten by caspase-3 during apoptosis.