Tenascin-X Antibodies

AND TNXB ELISA kits, Tenascin-X Proteins

Many biological assays use antibodies to detect Tenascin-X, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tenascin-X in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tenascin-X antibodies...

We validate the specificity of these antibodies to Tenascin-X by testing them on tissues known to express TNXB positively and negatively. Browse below to find the TNXB antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TNXB Infographic by Boster Bio

All TNXB Products

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Anti-TNXB Antibody Picoband®

1 Citations 3 Q&As

IHC analysis of TNXB using anti-TNXB antibody (PB9833)

Western blot analysis of TNXB using anti-TNXB antibody (PB9833)

IHC results in patients 1, 2, 7 and Immunofluorescence staining Patient 4

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # PB9833
100 μg/vial

Anti-Tenascin-X TNXB Antibody

Western blot analysis of extracts of various cell lines, using TNXB antibody at 1:1000 dilution

Mouse, Rat

$405
Cat # A03482
100ul

TNXB (NM_032470) Human Over-expression Lysate

Human

$960
Cat # LS007148
20 µg, 100 µg

TNXB Overview

Facts about Tenascin-X.

Tenascin-X (TNXB)

Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that seems to inhibit cell migration.

Accelerates collagen fibril formation. May play a role in supporting the development of epithelial tumors.

Gene Information

Human
Gene Name:	TNXB
Uniprot:	P22105
Entrez:	7148

Family

Belongs to:

tenascin family

Alternative Names

Hexabrachion-like protein; HXBL; Tenascin X; tenascin XB; tenascin XB2; tenascin-X; TNX; TNXB; TNXB1growth-inhibiting protein 45; TNXB2tenascin XB1; TNXBS; TNXBSTNXTENX; XB; XBS; XB-S; XBTN-X

Molecular Weight

Mass (kDA):
458.388 kDA

Genomic Context


Human

Location:	6p21.33-p21.32
Sequence:	6; NC_000006.12 (32041153..32109338, complement)

Tissue Specificity

Highly expressed in fetal adrenal, in fetal testis, fetal smooth, striated and cardiac muscle. Isoform XB- short is only expressed in the adrenal gland.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Hyperplasia
Ehlers-danlos Syndrome
Adrenal Hyperplasia
Congenital Adrenal Hyperplasia
Chronic Active Hepatitis
Malignant Neoplasms
Joint Laxity
Schizophrenia
Connective Tissue Diseases
Rheumatoid Arthritis
Dysequilibrium Syndrome
Arthritis

Carcinoma
Lupus Erythematosus, Systemic
Neoplasms
Arthritis, Juvenile Rheumatoid
Malignant Paraganglionic Neoplasm
Haploinsufficiency
Cystadenocarcinoma, Serous

Interacting Proteins

BANP

Pathways

Cell Cycle
Cell Activation
Cell Proliferation
Mitosis
Immune Response
B Cell Activation
Localization
Rna Splicing
Gene Conversion
Collagen Metabolic Process
Translation
Metabolic Process

Interphase
Wound Healing
Regulation Of Translation
Pathogenesis
Meiosis
Secretion

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNXB

References

PMID: 8530023 by Tee M.K., et al. Sequences promoting the transcription of the human XA gene overlapping P450c21A correctly predict the presence of a novel, adrenal-specific, truncated form of tenascin-X.

PMID: 7686164 by Bristow J., et al. Tenascin-X: a novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B.