TOX3 Antibodies

AND TOX3 ELISA kits, TOX3 Proteins

Many biological assays use antibodies to detect TOX3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TOX3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TOX3 antibodies...

We validate the specificity of these antibodies to TOX3 by testing them on tissues known to express TOX3 positively and negatively. Browse below to find the TOX3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TOX3 Infographic by Boster Bio

All TOX3 Products

Product

Figures

Specificity

Applications

Price

Anti-TOX3 / TNRC9 Monoclonal Antibody

7 Q&As

Human

ELISA, WB

$468
Cat # M06035
100ug/vial

TOX3 (NM_001080430) Human Over-expression Lysate

Human

$960
Cat # LS027324
100 µg

TOX3 Overview

Facts about TOX high mobility group box family member 3.

TOX3 3D structure. Source: alphafold

TOX high mobility group box family member 3 (TOX3)

Transcriptional coactivator of the p300/CBP-mediated transcription complex. Activates transactivation via cAMP response element (CRE) sites.

Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters.

Gene Information

Human
Gene Name:	TOX3
Uniprot:	O15405
Entrez:	27324

Family

Belongs to:

No superfamily

Alternative Names

CAG trinucleotide repeat-containing gene F9 protein; CAGF9trinucleotide repeat containing 9; TNRC9; TOX high mobility group box family member 3; Trinucleotide repeat-containing gene 9 protein

Molecular Weight

Mass (kDA):
63.342 kDA

Genomic Context


Human

Location:	16q12.1
Sequence:	16; NC_000016.10 (52436415..52547802, complement)

Tissue Specificity

Expressed mainly in epithelial cells. Expressed in the central nervous system (CNS), in the ileum and within the brain in the frontal and occipital lobe.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasm Of Breast
Malignant Neoplasms
Mammary Neoplasms
Neoplasms
Invasive Breast Carcinoma
Brca2 Gene Mutation
Neoplasm Invasiveness
Dysequilibrium Syndrome
Carcinoma Of Male Breast
Neoplasm Metastasis
Breast Neoplasms, Male
Female Breast Carcinoma

Sleep Disorders
Malignant Neoplasm Of Lung
Inflammatory Response
Carcinogenesis
Endoplasmic Reticulum Stress
Restless Legs Syndrome
Pancreatic Neoplasm

Pathways

Menarche
Methylation
Translation
Cell Death
Tissue Remodeling
Cell Differentiation
Dna Repair

Inflammatory Response

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TOX3

References

PMID: 9225980 by Margolis R.L., et al. cDNAs with long CAG trinucleotide repeats from human brain.

PMID: 21172805 by Dittmer S., et al. TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex.