This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Metalloprotease TIKI2 Antibodies
AND TRABD2B ELISA kits, Metalloprotease TIKI2 Proteins
Many biological assays use antibodies to detect Metalloprotease TIKI2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Metalloprotease TIKI2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Metalloprotease TIKI2 antibodies...
Previous: Septin9
Next: LDLRAD1
TRABD2B Infographic by Boster Bio
All TRABD2B Products
Product
Figures
Specificity
Applications
Price
TRABD2B Overview
Facts about Metalloprotease TIKI2.
Metalloprotease TIKI2 (TRABD2B)
Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N- terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.
Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.
Gene Information
| Human | |
|---|---|
| Gene Name: | TRABD2B |
| Uniprot: | A6NFA1 |
| Entrez: | 388630 |
Family
| Belongs to: |
|---|
| TIKI family |
Alternative Names
Metalloprotease TIKI2
Molecular Weight
Mass (kDA):
57.421 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p33 |
| Sequence: | 1; NC_000001.11 (47760528..47997385, complement) |
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Interacting Proteins
- Wnt3a
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRABD2B
bosterbio.com/bosterbio-gene-info-cards/TRABD2B
References
PMID: 22726442 by Zhang X., et al. Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation.