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- Table of Contents
Facts about Pro-thyrotropin-releasing hormone.
It promotes hair-shaft elongation, prolongs the hair cycle growth phase (anagen) and antagonizes its conclusion (catagen) by TGFB2. It stimulates proliferation and inhibits apoptosis of hair matrix keratinocytes.
Human | |
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Gene Name: | TRH |
Uniprot: | P20396 |
Entrez: | 7200 |
Belongs to: |
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TRH family |
MGC125964; MGC125965; prothyroliberin; thyrotropin-releasing hormone
Mass (kDA):
27.404 kDA
Human | |
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Location: | 3q22.1 |
Sequence: | 3; NC_000003.12 (129974720..129977935) |
Hypothalamus. Expressed in the hair follicle epithelium (at protein level).
Secreted.
PMID: 2126343 by Yamada M., et al. Cloning and structure of human genomic DNA and hypothalamic cDNA encoding human prepro thyrotropin-releasing hormone.
PMID: 19825978 by Gaspar E., et al. Thyrotropin releasing hormone (TRH): a new player in human hair- growth control.