TRH Antibodies

AND TRH ELISA kits, TRH Proteins

Many biological assays use antibodies to detect TRH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRH antibodies...

We validate the specificity of these antibodies to TRH by testing them on tissues known to express TRH positively and negatively. Browse below to find the TRH antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRH Infographic by Boster Bio

All TRH Products

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Product

Figures

Specificity

Applications

Price

Thyrotropin Releasing Hormone (TRH) (NM_007117) Human Over-expression Lysate

Human

$628
Cat # LS007200
20 µg, 100 µg

Anti-Trh Antibody Picoband®

Western blot analysis of Trh using anti-Trh antibody (A01108-2)

Mouse, Rat

$370
Cat # A01108-2
100 μg/vial

Anti-Danio rerio (Zebrafish) trh Antibody

Zebrafish

$470
Cat # DZ41880
200 μl/vial

TRH Overview

Facts about Pro-thyrotropin-releasing hormone.

TRH 3D structure. Source: alphafold

Pro-thyrotropin-releasing hormone (TRH)

As a component of this hypothalamic-pituitary-thyroid axis, it controls the secretion of thyroid-stimulating hormone (TSH) and is involved in thyroid hormone synthesis regulation. Additionally, it functions as modulator of hair growth.

It promotes hair-shaft elongation, prolongs the hair cycle growth phase (anagen) and antagonizes its conclusion (catagen) by TGFB2. It stimulates proliferation and inhibits apoptosis of hair matrix keratinocytes.

Gene Information

Human
Gene Name:	TRH
Uniprot:	P20396
Entrez:	7200

Family

Belongs to:

TRH family

Alternative Names

MGC125964; MGC125965; prothyroliberin; thyrotropin-releasing hormone

Molecular Weight

Mass (kDA):
27.404 kDA

Genomic Context


Human

Location:	3q22.1
Sequence:	3; NC_000003.12 (129974720..129977935)

Tissue Specificity

Hypothalamus. Expressed in the hair follicle epithelium (at protein level).

Subcellular Localizations

Secreted.

Diseases

Pituitary Diseases
Hypothyroidism
Pituitary Neoplasms
Neoplasms
Hyperthyroidism
Adenoma
Depressive Disorder
Nervousness
Acromegaly
Goiter
Hyperprolactinemia
Thyroid Diseases

Pituitary Adenoma
Primary Hypothyroidism
Graves Disease
Hypoglycemia
Diabetes Mellitus
Hypopituitarism
Major Depressive Disorder

Pathways

Secretion
Prolactin Secretion
Hormone Secretion
Localization
Growth Hormone Secretion
Pathogenesis
Transport
Excretion
Acid Secretion
Gastric Acid Secretion
Reflex
Virulence
Lactation

Aging
Innervation
Circadian Rhythm
Cortisol Secretion
Ovulation
Cell Proliferation
Gonadotropin Secretion

PTMs

Phosphorylation
Cleavage
Glycosylation
Amidation
Deamidation
Deiodination
Reduction
Methylation
Oxidation
Dephosphorylation

Iodination
Carboxylation
Biotinylation
Acetylation
Nitration
Palmitoylation
Ribosylation
Phosphorothioation
Acylation
Deacetylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRH

References

PMID: 2126343 by Yamada M., et al. Cloning and structure of human genomic DNA and hypothalamic cDNA encoding human prepro thyrotropin-releasing hormone.

PMID: 19825978 by Gaspar E., et al. Thyrotropin releasing hormone (TRH): a new player in human hair- growth control.