TRIM40 Antibodies

AND TRIM40 ELISA kits, TRIM40 Proteins

Many biological assays use antibodies to detect TRIM40, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRIM40 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRIM40 antibodies...

We validate the specificity of these antibodies to TRIM40 by testing them on tissues known to express TRIM40 positively and negatively. Browse below to find the TRIM40 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRIM40 Infographic by Boster Bio

All TRIM40 Products

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RNF35 (TRIM40) (NM_138700) Human Over-expression Lysate

Human

$628
Cat # LS135644
20 µg, 100 µg

Anti-TRIM40 Antibody Picoband®

Western blot analysis of TRIM40 using anti-TRIM40 antibody (A12141-3)

IHC analysis of TRIM40 using anti-TRIM40 antibody (A12141-3)

Human, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A12141-3
100 μg/vial

TRIM40 Overview

Facts about Tripartite motif-containing protein 40.

TRIM40 3D structure. Source: alphafold

Tripartite motif-containing protein 40 (TRIM40)

May be the E3 ubiquitin-protein ligase of the NEDD8 conjugation pathway. Promotes neddylation of IKBKG/NEMO, stabilizing NFKBIA, and inhibiting of NF-kappaB nuclear translocation and activity.

Gene Information

Human
Gene Name:	TRIM40
Uniprot:	Q6P9F5
Entrez:	135644

Family

Belongs to:

TRIM/RBCC family

Alternative Names

RING finger protein 35; ring finger RNF35; RNF35ring finger protein 40; tripartite motif containing 40; tripartite motif-containing 40; tripartite motif-containing protein 40

Molecular Weight

Mass (kDA):
29.336 kDA

Genomic Context


Human

Location:	6p22.1
Sequence:	6; NC_000006.12 (30135998..30148773)

Tissue Specificity

Highly expressed in normal gastrointestinal epithelia but that is down-regulated in gastrointestinal carcinomas and chronic inflammatory lesions of the gastrointestinal tract.

Diseases

Malignant Neoplasm Of Gastrointestinal Tract
Malignant Neoplasms
Autoimmune Reaction
Neoplasms
Chronic Inflammation
Gastrointestinal Neoplasms
Inflammation
Autoimmune Diseases

Dysequilibrium Syndrome
Carcinoma
Carcinogenesis

Pathways

Cell Growth

Research Areas

Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRIM40

References

PMID: 12622776 by Meyer M., et al. Cluster of TRIM genes in the human MHC class I region sharing the B30.2 domain.

PMID: 16702430 by Shiina T., et al. Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.