TMF-regulated nuclear protein 1 (Trnp1)

DNA-binding factor that regulates the expression of a subset of genes and plays a key role in tangential, radial, and lateral expansion of the brain neocortex. Regulates neural stem cells proliferation and the production of intermediate neural progenitors and basal radial glial cells affecting the process of cerebral cortex gyrification.

May control the proliferation rate of cells by regulating their progression through crucial cell-cycle transition points. .