Translin Antibodies

AND TSN ELISA kits, Translin Proteins

Many biological assays use antibodies to detect Translin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Translin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Translin antibodies...

We validate the specificity of these antibodies to Translin by testing them on tissues known to express TSN positively and negatively. Browse below to find the TSN antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TSN Infographic by Boster Bio

All TSN Products

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Product

Figures

Specificity

Applications

Price

TSN Colorimetric Cell-Based ELISA

Western blot analysis of extracts from Jurkat cells

Human, Mouse, Rat

ELISA

$480
Cat # EKC1824
1 kit, containing one 96-well plate and all necessary reagents

Human TSN Recombinant Protein

SDS-PAGE

$265
Cat # PROTQ15631
Starting from 20ug

Anti-Translin (TSN) Mouse Monoclonal Antibody [Clone ID: OTI1B5]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TSN (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 3 different cell lines by using anti-TSN monoclonal antibody (HepG2: human; HeLa: human; Jurkat: human; MCF7: human) (1:500)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TSN mouse monoclonal antibody

Human, Mouse, Rat

IHC, WB

$523
Cat # M02777
100 µl

Translin (TSN) (NM_004622) Human Over-expression Lysate

Human

$628
Cat # LS007247
20 µg, 100 µg

Anti-TSN Antibody Picoband®

Western blot analysis of TSN using anti-TSN antibody (A02777-3)

IHC analysis of TSN using anti-TSN antibody (A02777-3)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, WB

$370
Cat # A02777-3
100 μg/vial

TSN Overview

Facts about Translin.

TSN 3D structure. Source: alphafold

Translin (TSN)

DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.

Gene Information

Human
Gene Name:	TSN
Uniprot:	Q15631
Entrez:	7247

Family

Belongs to:

translin family

Alternative Names

BCLF-1; RCHF1; recombination hotspot associated factor; recombination hotspot-binding protein; REHF-1; TBRBP; translin; TRSLN

Molecular Weight

Mass (kDA):
26.183 kDA

Genomic Context


Human

Location:	2q14.3
Sequence:	2; NC_000002.12 (121755545..121767853)

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

Malignant Neoplasms
Chromosomal Translocation
Neoplasms
Infective Disorder
Carcinoma
Pneumonia
Mrsa - Methicillin Resistant Staphylococcus Aureus Infection
Escherichia Coli Infections
Urinary Tract Infection
Lung Neoplasms
Hypertrophy
Botulism

Liver Carcinoma
Nervousness
Tuberous Sclerosis
Fibrosis
Bacterial Infections
Gram-negative Bacterial Infections
Diabetes Mellitus

Interacting Proteins

GIT2
GORASP2
TSNAX

Pathways

Transport
Translation
Rna Interference
Localization
Mrna Transport
Spermatogenesis
Dna Recombination
Cell Cycle
Nuclear Transport
Secretion
Cell Division
Pachytene
Immune Response

Cell Death
Cell Activation
T Cell Activation
Nuclear Export
Cell Differentiation
Cell Proliferation
Dna Repair

PTMs

Cleavage
Phosphorylation
Sumoylation

Reduction
Oxidation
Methylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TSN

References

PMID: 7663511 by Aoki K., et al. A novel gene, Translin, encodes a recombination hotspot binding protein associated with chromosomal translocations.

PMID: 9244443 by Aoki K., et al. Genomic structure and chromosomal localization of the gene encoding translin, a recombination hotspot binding protein.