Tetraspanin-5 Antibodies

AND TSPAN5 ELISA kits, Tetraspanin-5 Proteins

Many biological assays use antibodies to detect Tetraspanin-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tetraspanin-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tetraspanin-5 antibodies...

We validate the specificity of these antibodies to Tetraspanin-5 by testing them on tissues known to express TSPAN5 positively and negatively. Browse below to find the TSPAN5 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TSPAN5 Infographic by Boster Bio

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TSPAN5 (NM_005723) Human Over-expression Lysate

Human

$628
Cat # LS010098
20 µg, 100 µg

TSPAN5 Overview

Facts about Tetraspanin-5.

TSPAN5 3D structure. Source: alphafold

Tetraspanin-5 (TSPAN5)

Regulates ADAM10 maturation and trafficking to the cell surface. Promotes ADAM10-mediated cleavage of CD44.

Gene Information

Human
Gene Name:	TSPAN5
Uniprot:	P62079
Entrez:	10098

Family

Belongs to:

tetraspanin (TM4SF) family

Alternative Names

member 8; NET4; tetraspanin 5; TM4SF9; TSPAN5; TSPAN-5

Molecular Weight

Mass (kDA):
30.337 kDA

Genomic Context


Human

Location:	4q23
Sequence:	4; NC_000004.12 (98470367..98658661, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Neoplasm Metastasis
Carcinoma
Neoplasm Invasiveness
Carcinogenesis
Multiple Myeloma
Trophoblastic Neoplasms
Nervousness
Hydatidiform Mole
Osteoporosis
Colorectal Cancer

Rheumatoid Arthritis
Cell Invasion
Cell Transformation, Neoplastic
Tissue Adhesions
Uterine Neoplasms
Hydatidiform Mole, Invasive
Precursor T-cell Lymphoblastic Leukemia-lymphoma

Interacting Proteins

ADAM10

Pathways

Cell Adhesion
Cell Proliferation
Cell Migration
System Development
Cell Cycle
Cell Motility
Nervous System Development
Brain Development
Bone Remodeling

Cell Growth
Rna Interference
Oogenesis

PTMs

Cleavage

Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TSPAN5

References

PMID: 9714763 by Todd S.C., et al. Sequences and expression of six new members of the tetraspanin/TM4SF family.

PMID: 26686862 by Jouannet S., et al. TspanC8 tetraspanins differentially regulate the cleavage of ADAM10 substrates, Notch activation and ADAM10 membrane compartmentalization.