TSPEAR Antibodies

AND TSPEAR ELISA kits, TSPEAR Proteins

Many biological assays use antibodies to detect TSPEAR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TSPEAR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TSPEAR antibodies...

We validate the specificity of these antibodies to TSPEAR by testing them on tissues known to express TSPEAR positively and negatively. Browse below to find the TSPEAR antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TSPEAR Infographic by Boster Bio

All TSPEAR Products

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TSPEAR (NM_144991) Human Over-expression Lysate

Human

$960
Cat # LS054084
20 µg, 100 µg

TSPEAR Overview

Facts about Thrombospondin-type laminin G domain and EAR repeat-containing protein.

TSPEAR 3D structure. Source: alphafold

Thrombospondin-type laminin G domain and EAR repeat-containing protein (TSPEAR)

May play a role in development or function of the auditory system. .

Gene Information

Human
Gene Name:	TSPEAR
Uniprot:	Q8WU66
Entrez:	54084

Family

Belongs to:

No superfamily

Alternative Names

C21orf29; Chromosome 21 Open Reading Frame 29; Deafness, Autosomal Recessive 98; DFNB98; Thrombospondin Type Laminin G Domain And EAR Repeats; Thrombospondin-Type Laminin G Domain And EAR Repeat-Containing Protein; Thrombospondin-Type Laminin G Domain And EAR Repeats-Containing Protein; TSP-EAR

Molecular Weight

Mass (kDA):
74.924 kDA

Genomic Context


Human

Location:	21q22.3
Sequence:	21; NC_000021.9 (44497893..44711572, complement)

Subcellular Localizations

Secreted. Cell surface. Cell projection, stereocilium. Secreted protein which may bind to the cell surface via a membrane receptor.

Diseases

Epilepsy
Complete Hearing Loss
Mood Disorders
Impairment (finding)
Sensorineural Hearing Loss (disorder)
Tissue Adhesions

Bipolar Disorder

Pathways

Response To Oxidative Stress
Platelet Aggregation
Secretion

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TSPEAR

References

PMID: 12095917 by Scheel H., et al. A common protein interaction domain links two recently identified epilepsy genes.

PMID: 22678063 by Delmaghani S., et al. Defect in the gene encoding the EAR/EPTP domain-containing protein TSPEAR causes DFNB98 profound deafness.