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- Table of Contents

Facts about Testis-specific serine/threonine-protein kinase 1.
Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.
| Human | |
|---|---|
| Gene Name: | TSSK1B |
| Uniprot: | Q9BXA7 |
| Entrez: | 83942 |

| Belongs to: |
|---|
| protein kinase superfamily |

EC 2.7.11; serine/threonine kinase 22D (spermiogenesis associated); Serine/threonine-protein kinase 22A; spermiogenesis associated 4; SPOGA1; SPOGA4EC 2.7.11.1; STK22A; STK22DFKSG81; Testis-specific kinase 1; testis-specific serine kinase 1; testis-specific serine kinase 1B; testis-specific serine/threonine-protein kinase 1; TSK-1; TSSK-1; TSSK1serine/threonine kinase FKSG81
Mass (kDA):
41.618 kDA

| Human | |
|---|---|
| Location: | 5q22.2 |
| Sequence: | 5; NC_000005.10 (113432553..113434989, complement) |
Testis-specific. Present in sperm (at protein level).
Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome. Cell projection, cilium, flagellum. In spermatozoa, present in the sperm head and in the flagellum.





PMID: 15044604 by Hao Z., et al. Expression analysis of the human testis-specific serine/threonine kinase (TSSK) homologues. A TSSK member is present in the equatorial segment of human sperm.
PMID: 15733851 by Jaleel M., et al. Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate.