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- Table of Contents
TTF2 Antibodies
AND TTF2 ELISA kits, TTF2 Proteins
Many biological assays use antibodies to detect TTF2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TTF2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TTF2 antibodies...
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TTF2 Infographic by Boster Bio
All TTF2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A04344-2
100 μg/vial
Cat # A04344-2
100 μg/vial
TTF2 Overview
Facts about Transcription termination factor 2.
Transcription termination factor 2 (TTF2)
DsDNA-dependent ATPase which functions as a transcription termination factor by coupling ATP hydrolysis with elimination of RNA polymerase II in the DNA template. May contribute to mitotic transcription repression.
May also be involved in pre-mRNA splicing. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TTF2 |
| Uniprot: | Q9UNY4 |
| Entrez: | 8458 |
Family
| Belongs to: |
|---|
| SNF2/RAD54 helicase family |
Alternative Names
EC 3.6.1; EC 3.6.4.-; F2; HuF2lodestar protein; human factor 2; Lodestar homolog; RNA polymerase II termination factor; Transcription release factor 2; transcription termination factor 2; transcription termination factor, RNA polymerase II
Molecular Weight
Mass (kDA):
129.588 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p13.1 |
| Sequence: | 1; NC_000001.11 (117060303..117107453) |
Subcellular Localizations
Cytoplasm. Nucleus. Cytoplasmic during interphase. Relocates to the nucleus as cells enter mitosis.
Diseases
- Hypothyroidism
- Congenital Hypothyroidism
- Congenital Abnormality
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Congenital Absence
- Cleft Palate
- Thyroid Neoplasm
- Hypoplasia
- Malignant Paraganglionic Neoplasm
- Choanal Atresia
Interacting Proteins
- CDC5L
Pathways
- Transport
- Gland Development
- Localization
- Cell Growth
- Thyroid Gland Development
- Iodide Transport
- Mitosis
- Dna Repair
- Chromosome Segregation
- Inflammatory Response
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TTF2
bosterbio.com/bosterbio-gene-info-cards/TTF2
References
PMID: 9748214 by Liu M., et al. A human RNA polymerase II transcription termination factor is a SWI2/SNF2 family member.
PMID: 12927788 by Leonard D., et al. hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing.