TTI2 Antibodies

AND TTI2 ELISA kits, TTI2 Proteins

Many biological assays use antibodies to detect TTI2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TTI2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TTI2 antibodies...

We validate the specificity of these antibodies to TTI2 by testing them on tissues known to express TTI2 positively and negatively. Browse below to find the TTI2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: TMEM134

TTI2 Infographic by Boster Bio

All TTI2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

C8ORF41 (TTI2) (NM_025115) Human Recombinant Protein

Coomassie blue staining of purified TTI2 protein

$1249
Cat # PROTQ6NXR4
20 µg

C8ORF41 (TTI2) (NM_001102401) Human Over-expression Lysate

C8ORF41 (TTI2) Human Over-expression Lysates NM_001102401

Human

$960
Cat # LS080185
20 µg, 100 µg

Anti-TTI2 Antibody Picoband®

Western blot analysis of TTI2 using anti-TTI2 antibody (A12943-1)

Flow Cytometry analysis of U251 cells using anti-TTI2 antibody (A12943-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A12943-1
100 μg/vial

TTI2 Overview

Facts about TELO2-interacting protein 2.

TTI2 3D structure. Source: alphafold

TELO2-interacting protein 2 (TTI2)

Regulator of the DNA damage response (DDR). Part of this TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins.

The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complicated and HSP90 may participate in the proper folding of newly synthesized PIKKs.

Gene Information

Human
Gene Name:	TTI2
Uniprot:	Q6NXR4
Entrez:	80185

Family

Belongs to:

TTI2 family

Alternative Names

C8orf41; chromosome 8 open reading frame 41; FLJ23263; hypothetical protein LOC80185; TELO2 interacting protein 2; TTI2

Molecular Weight

Mass (kDA):
56.915 kDA

Genomic Context


Human

Location:	8p12
Sequence:	8; NC_000008.11 (33498722..33513135, complement)

Diseases

Ataxia
Retinopathy Of Prematurity

Pathways

Telomere Maintenance

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TTI2

References

PMID: 20810650 by Hurov K.E., et al. A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.

PMID: 20801936 by Takai H., et al. Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.