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- Table of Contents
Twist-related protein 1 Antibodies
AND TWIST1 ELISA kits, Twist-related protein 1 Proteins
Many biological assays use antibodies to detect Twist-related protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Twist-related protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Twist-related protein 1 antibodies...
Designing a Western blot for Twist-related protein 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TWIST1 Western Blot GuideTWIST1 Infographic by Boster Bio
All TWIST1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # A00980-1
100 μg/vial
Cat # A00980-1
100 μg/vial
Human, Mouse, Rat
ELISA, IP, IF, WB
$146
Cat # M00980-1
20μL, 40μL, 100μL, 200μL
Cat # M00980-1
20μL, 40μL, 100μL, 200μL
TWIST1 Overview
Facts about Twist-related protein 1.
Twist-related protein 1 (TWIST1)
Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the fundamental domains of both proteins.
Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion.
Gene Information
| Human | |
|---|---|
| Gene Name: | TWIST1 |
| Uniprot: | Q15672 |
| Entrez: | 7291 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
acrocephalosyndactyly 3; ACS3; B-HLH DNA binding protein; BHLHA38; bHLHa38BPES3; BPES3; Class A basic helix-loop-helix protein 38; CRS1; H-twist; H-twistblepharophimosis, epicanthus inversus and ptosis 3; SCSBPES2; twist homolog 1 (Drosophila); TWIST homolog of drosophila; TWIST; Twist1; Twist-1; twist-related protein 1
Molecular Weight
Mass (kDA):
20.954 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7p21.1 |
| Sequence: | 7; NC_000007.14 (19113047..19117636, complement) |
Tissue Specificity
Subset of mesodermal cells.
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Neoplasm Metastasis
- Carcinoma
- Cell Invasion
- Craniosynostosis
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Saethre-chotzen Syndrome
- Neoplasm Invasiveness
- Acrocephalosyndactylia
- Cell Transformation, Neoplastic
Interacting Proteins
- BRD4
- ETS2
- G3BP2
- KAT2B
- KAT5
- KMT5A
- TCF4
- TP53
Pathways
- Methylation
- Cell Migration
- Cell Proliferation
- Osteoblast Differentiation
- Dna Methylation
- Cell Growth
- Epithelial To Mesenchymal Transition
- Cell Motility
- Pathogenesis
- Cell Differentiation
- Angiogenesis
- Localization
- Cell Death
PTMs
- Methylation
- Phosphorylation
- Acetylation
- Demethylation
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TWIST1
bosterbio.com/bosterbio-gene-info-cards/TWIST1
References
PMID: 9073070 by Wang S.M., et al. Cloning of the human twist gene: its expression is retained in adult mesodermally-derived tissues.
PMID: 8995765 by Bourgeois P., et al. The human H-twist gene is located at 7p21 and encodes a B-HLH protein that is 96% similar to its murine M-twist counterpart.
1 Publications of Boster Twist-related protein 1 Antibodies & ELISA Kits
- PubMed ID: 33237234, Rolim LSA, Mafra RP, Santos HBP, Souza LB, Pinto LP. Role of Twist and Podoplani...
*More publications can be found for each product on its corresponding product page