Thioredoxin reductase 3 Antibodies

AND TXNRD3 ELISA kits, Thioredoxin reductase 3 Proteins

Many biological assays use antibodies to detect Thioredoxin reductase 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Thioredoxin reductase 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Thioredoxin reductase 3 antibodies...

We validate the specificity of these antibodies to Thioredoxin reductase 3 by testing them on tissues known to express TXNRD3 positively and negatively. Browse below to find the TXNRD3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TXNRD3 Infographic by Boster Bio

All TXNRD3 Products

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TXNRD3IT1 (TXNRD3NB) (NM_001039783) Human Over-expression Lysate

Human

$628
Cat # LS645840
20 µg, 100 µg

Human TXNRD3NB Recombinant Protein

SDS-PAGE

$293
Cat # PROTQ6F5E7
Starting from 10ug

TXNRD3 Overview

Facts about Thioredoxin reductase 3.

Thioredoxin reductase 3 (TXNRD3)

Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization.

Promotes disulfide bond formation between GPX4 and various sperm proteins and might play a role in sperm maturation by promoting formation of semen structural components (By similarity). .

Gene Information

Human
Gene Name:	TXNRD3
Uniprot:	Q86VQ6
Entrez:	114112

Family

Belongs to:

class-I pyridine nucleotide-disulfide oxidoreductase family

Alternative Names

TGR; thioredoxin reductase 3; TR2; TRXR3

Molecular Weight

Mass (kDA):
70.683 kDA

Genomic Context


Human

Location:	3q21.3
Sequence:	3; NC_000003.12 (126607059..126655124, complement)

Subcellular Localizations

Cytoplasm. Nucleus. Microsome. Endoplasmic reticulum. Detected in cytoplasm and nucleus in late spermatids.

Diseases

Malignant Neoplasms
Carcinoma
Liver Diseases
Drug-induced Liver Injury
Melanoma
Respiratory Distress Syndrome, Adult
Infectious Mononucleosis
Malignant Neoplasm Of Breast
Colonic Neoplasms
Malignant Tumor Of Colon
Ulceration Of Intestine
Pre-eclampsia

Teratogenic Effect
Respiratory Distress
Fetal Growth Retardation
Ulcer
Vascular System Injuries
Neoplasms

Pathways

Cell Death
Cell Growth
Cell Proliferation
Programmed Cell Death
Regulation Of Signal Transduction
Proteolysis
Regeneration
Regulation Of Histone Acetylation
Translation
Cell Cycle

Protein Folding
Histone Acetylation
Pathogenesis
Apoptotic Process
Excretion

PTMs

Oxidation
Phosphorylation

Reduction
Acetylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TXNRD3

References

PMID: 10455115 by Sun Q.-A., et al. Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases.

PMID: 20018845 by Gerashchenko M.V., et al. CUG start codon generates thioredoxin/glutathione reductase isoforms in mouse testes.